Anti-bacterial Activity of Garlic Extracts

Original article


R. C. Jain 1, Mahmoub A. El-Khani 2, Essa M. Abdulla 2

1-Department of Pathology, Faculty of Medicine, University of Garyounis, Benghazi. 2-Department of Microbiology and Parasitology, Faculty of Medicine, Garyounis, Benghazi.

Garyounis Medical Journal Vol. 1, No.1. January 1978:11-14


The antibacterial activity of garlic oil on 23 selected bacteria was demonstrated in vitro. The effect of two ether extracts (2.83 and 3.33 mg allicin/disc) on growth as measured by zones of inhibition in agar cultures was obtained with C. diphtheriae, Ps. aeruginosa, and representative species of Salmonella, Shigella, Proteus, Streptococci and Staphylococci, as well as with some human commensals. The inhibitory effect of two lesser concentrations of garlic oil with antibacterial activity (1.5 and 2.0mg allicin/disc) on 11 of 13 bacteria tested was found to be significant in comparison to the range of action of 10 commercial antibiotics. Extracts prepared with ethyl alcohol or distilled water did not give satisfactory zones of inhibition.

Keywords: Anti-bacterial Activity of Garlic Extracts