Association of a Retroperitoneal Liposarcoma and an Adrenal Medullary Hyperplasia Feigning a Pheochromocytoma

Case report


Fehmi Hamila 1, Mohamed Salah Jarrar 1, Khalil Tarmiz 2, Abdelmejid Khenissi 1, Abdelmejid Mselmi 1, Dhafer Beltaifa 2, Jaballah Sakhri 1, Rached Letaief 1

1- General Surgery Department and 2 -Anaesthesiology Department, Farhat Hached Universitary Hospital, Sousse, Tunisia

JMJ Vol.7, No.3 (Autumn 2007):229-230


A 45-year old woman presented with a recent paroxysmal hypertension and a flush syndrome. Physical examination revealed an abdominal mass with positive left lumbar contact. The urine metanephrine was high. The CT scan and the Magnetic Resonance Imaging (MRI) showed a 10 cm retroperitoneal tumour apart from the left adrenal gland and driving back the left kidney. The diagnosis of ectopic pheochromocytoma was suspected and the patient was operated. A tumour resection widened to the left adrenal gland and to the kidney was performed. The specimen histology showed a well-differentiated liposarcoma associated to an adrenal medullary hyperplasia (AMH). Postoperatively blood pressure was stabilized at normal levels. The review of literature show that AMH mimicking a pheochromocytoma is rare and its association with a giant retroperitoneal liposarcoma has never been reported before.

Keywords: Liposarcoma, Retroperitoneum, Adrenal medullary hyperplasia, Pheochromocytoma