Bone mineral density in patients with chronic hypoparathyroidism

Original article

English

Salem Abugassa, Jorgen Nordenstrom, Staffan Eriksson, and Goran Sjoden

Department of Surgery (S.A., J.N.) and Orthopaedic Surgery (S.E., G.S.), Huddinge University Hospital, Huddinge, Sweden

JMJ Vol. 2. No.1 [March] 2002: 51-56

Abstract

Photon adsorptiomety was used to measure skeletal mass in the proximal femur, lumber spine and distal radius in 19 females, with hypoparathyroidism following operation either for thyroid carcinoma or hyperparathyroidism. Healthy subjects as well as normo-calcemic patients who had undergone the same surgical procedure without developing hypoparathyroidism were used as control. Skeletal mass was mean measured after a mean postoperative time of 13and 10years in patients operated on for thyroid carcinoma and hypoparathyroid patients than in the controls. In patients with retained parathyroid function after total thyroidectomy and after surgical treatment of hyperparathyroidism bone mass did not differ from that in age –matched healthy controls. Long-term thyroxin medication in doses that suppressed endogenous thyroid stimulating hormone production (TSH) was not associated with a decreased bone mass. Reduced parathyroid hormone (PTH) production, vitamin D treatment, and calcium supplementation may all have contributed to the increased bone mass found in the patients with postsurgical hypoparathyroidism.

Keywords: Photon adsorptiomety, Hypoparathyroidism

Link/DOI: http://www.jmj.org.ly/modules.php?name=News&file=article&sid=1219