A.S.M. Giasuddin, I.A. Shaafie, M.M. Ziu
Department of Laboratory Medicine, Al-Arab Medical University, Benghazi, G. S.P.L.A.J.
Garyounis Medical Journal Vol.12, No.1-2. January 1989:52-54
During the outbreak of human brucellosis in Benghazi, Libya, in June-September 1987, haematological and biochemical parameters were analysed in 18 Libyan patients (age: 16:60 years; sex: 10 male, 8 female). Since leukopenia with relative lymphocytosis was present in 5/18 (28%) patients only, it was not considered as a general rule for diagnosis of acute brucellosis. The ESR was raised in 14/18 (78%) patients which is generally a feature of acute brucellosis. Although biochemical analyses showed in some cases moderate elevation of serum ALT (8/18), AST (7/18), ALP (2/18) and LDH (5/18), serum ALT, AST and LDH were markedly elevated in only 5/18 (28%), 6/18 (33%) and 3/16 (18%) patients respectively. The implications of these findings and methods of choice for quick and confirmed diagnosis of acute brucellosis as a possible cause for pyrexia of unknown origin are discussed.
Keywords: Clinical, Biochemical and Haematological Features of an Outbreak of Human Brucellosis in Benghazi