Extended Spectrum ك-Lactamases (ESBL): Missing the Target by Both Laboratorians and Clinicians



Abdulaziz Zorgani

Department of Microbiology and Immunology, Faculty of Medicine, Al-Fateh Medical University, Tripoli, Libya

JMJ 2009,Vol.9, No.3: 177-183


The prevalence of extended spectrum ك-lactamases (ESBL) producing organisms is increasing worldwide and several outbreaks have been reported. The emergence of ESBL outbreaks creates a significant challenge for both clinical microbiology laboratories and clinicians. The former lack the skills, experience and the capacity to detect ESBLs producing organisms. The latter are not aware of the challenges and risk factors associated with these organisms, proper therapeutic options and implementation of infection control measures. These challenges must be seriously addressed by all health care institutions by establishing proper detection systems to monitor the prevalence of ESBL to define the magnitude of the problem and to implement appropriate infection control measures. The aim of this report is to increase awareness of this serious antibiotic resistance threat.

Keywords: ESBL, Laboratory, Clinicians, Antibiotic, Therapy.

Link/DOI: http://www.jmj.org.ly/PDF/autumn2009/177.pdf