Familial occurrence of congenital incomplete prepyloric mucosal diaphragm.

Case report

English

Gahukamble DB.

Department of Paediatric Surgery, Faculty of Medicine, Al-Arab Medical University, Benghazi, Libya.

J Med Genet. 1998 Dec;35(12):1040-2.

Abstract

Incomplete prepyloric mucosal diaphragm (IPMD) is an uncommon congenital anomaly that leads to gastric outlet obstruction in infancy and childhood. This report describes the occurrence of IPMD in six children in a closely knit tribal family from a geographically isolated desert town with a small population in the Sahara. Their records showed similarities of clinical, radiological, operative, and histopathological features. These features, as well as its occurrence in brothers, sisters, and cousins, suggest that this unusual anomaly is transmitted as an autosomal recessive trait.

Keywords: Incomplete prepyloric mucosal diaphragm ,IPMD,Gastric Outlet Obstruction

Link/DOI: http://jmg.bmj.com/cgi/content/abstract/35/12/1040