M.S. Elsaiti MD, S.E. Gerryo MD, FRCP
Department of Medicine and Endocrinology,
Jamahiriya Hospital, Benghazi, Libya
JMJ Vol. 1, No. 2 (November 2001): 77-78
Fibrodysplasia ossificans progressive (fop) is a rare autosomal dominant disease characterized by progressive ossification of striated muscles. Secondary amenorrhea is described as an uncommon feature. This case report described a 24- years old female patient with FOP and primary amenorrhea who failed to have withdrawal bleeding after two courses of estrogen-progesterone challenge therapy in spite of normal pituitary ovarian function. To clarify possible explanation for the association between FOP and primary amenorrhea further studies are needed.
Keywords: primary amenorrhea, Fibrodysplasia Ossification