E. M. Abdulla 2, M. Shahabuddin 2, M. J. Akhtar 1
1-Department of Microbiology and Parasitology, Faculty of Medicine, University of Garyounis, Benghazi, S.P.L.A.J. 2-Department of Microbiology, Faculty of Science, University of Karachi, Pakistan, and formerly Faculty of Medicine, University of Garyounis, Benghazi, S.P.L.A.J.
Garyounis Medical Journal Vol. 4, No.2. July 1981:49-54
Oral griseofulvin proved effective in aborting the clinical course of herpes labialis infection in 30/31 patients (96.77%) when administered during the prodromalperiod or up to 20 hours following commencement of symptoms at the usual site of reinfection. The drug had no effect when commenced 48 hours or later after onset. While griseofulvin shortened the length of genital herpes episodes, idoxuridine lotion proved to be highly effective in all 5 such patients, significantly reducing or negating the progress of blisters. Both drugs, however, did not prevent the recurrence of infection. Contemporary reported measures for handling herpes simplex virus infection are reviewed.
Keywords: Griseofülvin for Herpes Simplex Infection. A Clinical Trial with 38 Patients