Klebsiella pneumoniae harbouring OXA-48 carbapenemase in a Libyan refugee in Italy



Kocsis E, Savio C, Piccoli M, Cornaglia G, Mazzariol A.


Clin Microbiol Infect. 2013 Sep;19(9):E409-11. doi: 10.1111/1469-0691.12232. Epub 2013 May 9.


A carbapenem-resistant Klebsiella pneumoniae was isolated from a blood-culture of an inpatient from Libya, hospitalized in the intensive-care unit of Negrar Hospital, Italy. The clinical isolate carried the following β-lactamase genes, bla(TEM -1), bla(SHV -11), bla(OXA -1), bla(CTX -M-15) and bla(OXA -48), respectively. The bla(OXA -48) gene was inserted in the Tn1999.2 transposon type, carried on a conjugative, 60-kilobase plasmid, that presented an L/M backbone, hosted by a multidrug-resistant ST 101 K. pneumoniae strain. Our report highlights the international transfer of bla(OXA -48) gene and the importance of screening measures of multidrug-resistant Enterobacteriaceae. CI – © 2013 The Authors Clinical Microbiology and Infection © 2013 European Society of Clinical Microbiology and Infectious Diseases.

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Link/DOI: 10.1111/1469-0691.12232