Malaria and failure of chloroquine prophylaxis: Our experience

Original article


Ahmed F. El-Hassi, Mohamed Bushaala Ali, Ahmed A. Toweir, Farag S. Ali

Infectious Disease Unit, Jamahiriya Hospital, Benghazi

JMJ Vol. 1, No. 1 (June 2001): 27-29


A total of 20 Libyan citizens infected with Plasmodium Falciparum malaria acquired through travel to malaria endemic areas in some African countries were evaluated for the failure of chloroquine prophylaxis recommended to them during their stay abroad.
Chloroquine resistance was suggested by the development of malaria due to Plasmodium Falciparum despite their intake of chloroquine. Their classic malaria symptoms responded to mefloquine therapy very well. We would like to stress the use of an alternative chemoprophylaxis other than chloroquine for travellers to neighbouring African countries due to the spread of Plasmodium Falciparum resistance to chloroquine in the area.

Keywords: Plasmodium Falciparum, Chloroquine prophylaxis, chloroquine resistance, and mefloquine