P. Bhatt, S. Vohra, A. M. Layas
Libyan Swiss Diagnostic Centre, Tripoli, Libya
JMJ Vol.3 No.2 (September) 2004: 92-94
Pigmented villonodular synovitis (PVNS) is a rare proliferative disorder of the synovial membrane, of obscure etiology, exhibiting benign behaviour from a biological point of view, with a wide spectrum of clinical presentations and imaging findings. This kind of synovial hyperplasia leads to the formation of villi and nodules characterized by deposit of intracellular haemosiderin. It primarily involves young adults, the peak age being between the second and fourth decade of life. PVNS involves young adults, with no gender preference; it affects the knee joint in 66-80% of cases, with no typical symptomatology. The joint most affected is the knee and diffuse PVNS is the most common form. Diagnostic imaging techniques, particularly MRI, allow lesion identification, suggesting a diagnosis. However, such diagnosis can be confirmed only on histology as the final diagnosis of PVNS, and therefore the possibility of differential diagnosis with other hemorrhagic and chronic hyperplastic synovitis, is based on the detection of intracellular haemosiderin components.[1,2] .We present a case of pathologically proven PVNS to characterize the magnetic resonance imaging (MRI) features of PVNS. The radiographs, computed tomography (CT) and magnetic resonance (MR) images are presented with emphasis on MR images.
Keywords: Hemosiderin – Magnetic resonance imaging – Pigmented villonodular synovitis Abbreviations: PVNS Pigmented villonodular synovitis. GRE:Gradient Recalled Echo