New pyrrole alkaloids from Solanum sodomaeum.

Original article

English

El Sayed KA, Hamann MT, Abd El-Rahman HA, Zaghloul AM.

The Department of Pharmacognosy and National Center for the Development of Natural Products and Research Institute of Pharmaceutical Sciences, University of Mississippi, University, Mississippi 38677, USA. elsayed@olemiss.edu

J Nat Prod. 1998 Jun 26;61(6):848-50.

Abstract

Two new pyrrole alkaloids, solsodomine A and B, were isolated from the fresh berries of Solanum sodomaeum L., collected from the Libyan desert. The structures of these compounds were established by 2D-NMR, including 15N NMR spectroscopy and chemical degradation. Solsodomine A (1) shows activity against Mycobacterium intracellulare. This is the first report of pyrrole alkaloids from the genus Solanum.

Keywords: Solanum sodomaeum,pyrrole alkaloid,desert,Mycobacterium

Link/DOI: http://pubs.acs.org/cgi-bin/abstract.cgi/jnprdf/1998/61/i06/abs/np980042p.html