Occurrence of Chromoblastomycosis due to Cladophialophora carrionii in a Libyan patient

Case report


Zendah B 1, Elgaed K 1, Kavanagh K 4, Zorgani AA 3, Ellabib MS 2, 3

1-Dermatology Department, Tripoli Medical Centre. 2-Mycology section, Tripoli Medical Centre, 3-Department of Medical Microbiology, Medical College, Al-Fateh University, Tripoli, Libya. 4-Medical Mycology Unit, Department of Biology, National University of Ireland Maynooth, Co.Kildare, Ireland.

Libyan J Infect Dis. 2009;3(1):65-68


In this study we report the second occurrence of chromoblastomycosis in Libya and identify the etiological agent.
A 60 year old woman, presented with a history of asymptomatic left upper limb multiple skin lesions which had healed with scars. The lesions started at the site of a previous trauma to the left hand and after a few years had spread to involve the left forearm. Upon examination non-tender multiple erythematous, verrucous infiltrated plaques on the left hand and forearm were seen. Some lesions healed with atrophic and ivory coloured scar tissue. Skin biopsy with H&E stain demonstrated pseudoepitheliomatous
hyperplasia of the epidermis, with micro abscesses and a diffuse lymph mononuclear inflammatory cell. In the upper dermis thick walled coloured fungal cells were seen inside and outside the giant cells. Fungal culture showed a slow-growing dark black velvety colony. The macro and micro morphology of Cladophialophora carrionii was noted.

Keywords: Chromoblastomycosis. Cladophialophora carrionii, Libya.