Organophosphorous poisoning

Original article


H. Belazi, K. Shalabi, S. Mletan

Department of Paediatrics Elfateh University Tripoli Libya
Tripoli Children Hospital, Tripoli- Libya

JMJ Vol.3 No.2 (September) 2004: 78-79


Objectives: To find out the incidence, clinical profile and medical management of organophosphorous poisoning. Method and Patients: We reviewed retrospectively the medical files of PICU patients over the period 01/ 07 / 2000 – 30 /06 / 2001 in Tripoli Children Hospital. The review included history, clinical presentation, management and outcome. Results: Total number of PICU admissions was 295 children. Nine of them were due to organophosphorous poisoning (3% of total PICU admissions) Clinical Presentations: The history of organophosphorous was present in 9 children (100%). Clinical Profile: Miosis 100%, Lethargy 78%, Muscular Weakness 56%, Salivation 56%, Vomiting 56%, Depressed Mental State 44%, Diarrhoea 22%. Diagnosis was based on only history and clinical examination. The average duration in PICU stay 4.2 days. All of them were treated successfully by Atropine. The number of Atropine dosages per patients ranged from 6 to73 doses. Conclusion: In any patient presents with meiosis, lethargy, muscular weakness and vomiting, organophosphorous poisoning has to be excluded. Using cholinesterase assay confirm the assumptive of our current clinical diagnosis. Atropine remains the main therapy for organophosphorous poisoning.

Keywords: Organophosphorous, meiosis, lethargy