Regional wall motion changes following percutaneous coronary intervention of patient with acute coronary syndrome: Short-term follow-up

Original article


A. Abdellatief Hussain, Y. Baghdady, M. Abdelghany, S. Eltobgy

Cardiology Department, Cairo University, Cairo, Egypt

JMJ Vol. 2, No. 3 (March 2003): 18-22


Abnormal left ventricular (LV) function is the major predictor of mortality after acute myocardial infarction. In patients (pts) with acute coronary syndrome (ACS), Percutaneous coronary intervention (PCI) may improve ventricular function including regional wall motion and consequently, prognosis. The aim of this study was to evaluate regional wall motion following PCI in pts with ACS. Forty patient (mean age =49±9 years), presenting with ACS who underwent successful PCI for single vessel significant CAD, with uneventful one month follow-up period were included in the study. Resting Echocardiographic Assessment of regional systolic function revealed significant improvement in segmental wall motion score index (SWMSI: 1.5± 0.3,pre –PCI, to 1.3±0.3 post-PCI) (p<0.001). In addition, 72.5% of studied patient population showed Improvement in the wall thickness percentage (WT %) in the revascularized region. Also, there was significant decrease in the end-systolic volume from82±30.1ml to 75±26ml (p<0.05), however, the change in the end –diastolic volume was insignificant, 138±45 ml to 138 ±46 ml (0.05). There was also significant improvement in the ejection fraction (EF) (40±11% pre-PCI to 47±12 post-PCI, p<0.05). Diastolic function did not change before or after angioplasty. Conclusion: regional and global LV systolic function improved significantly at 1 month following PCI. Pts with the most impaired baseline global LV systolic function exhibited the greatest improvement in the EF post-PCI Keywords: Percutaneous coronary intervention, acute coronary syndrome, echocardiography, regional wall motion abnormality, left ventricular function Ejection Fraction Link/DOI: