Seroprevalence of Cytomegalovirus infections among blood donors in Benghazi

Original article


R. R. Elmehdawi, A. Alaysh

Jamahiriya Hospital, Benghazi – Libya

JMJ Vol. 2, No. 2 (September 2002): 58-60


Transfusion of blood components containing viable leukocytes infected with Human Cytomegalovirus (HCMV) may transmit the virus, which will persist lifelong in the recipient leukocytes. This infection carries special risk to immunocompromised individuals, foetuses and low birth weight infants. The aim of this study is to define the prevalence rate of HCMV seropositivity among blood donors in Benghazi city. During December -2000, 170 blood donors of Libyan nationality of ages 18-47 years were randomly selected and their sera were analyzed qualitatively for the presence of HCMV antibodies using the passive latex agglutination test (PLA) the data were analyzed statistically using ANOVA test and Chi – square test. Prevalence rate of HCMV seropositivity in blood donors in Benghazi is 50.6% and there is no significant difference between different age groups.

Keywords: Human Cytomegalovirus (HCMV), Seropositivity, immunocompromised, CMV, blood donors.