Simultaneous pancreas-kidney transplantation at the Ohio State University Medical Center.

Original article

English

Elkhammas EA, Henry ML, Yilmaz S, Pelletier RP, Bumgardner GL, Ferguson RM.

Ohio State University, College of Medicine, Department of Surgery, Columbus, USA.

Clin Transpl. 1997;:167-72.

Abstract

Simultaneous pancreas-kidney transplantation is possible in a large number of Type I diabetics with excellent patient and graft survival. Diabetic patients are prone to coronary artery disease (CAD) which remains the most common cause of death in both the pre- and posttransplant periods. Exclusion of significant CAD and/or cardiac dysfunction in the potential recipient is necessary. At The Ohio State University, one-year patient, pancreas and kidney graft survival rates were 92%, 80%, and 84%, respectively. Acute rejection following simultaneous pancreas-kidney transplantation remains a major problem but has been positively affected by newer agents. Enteric conversion is needed in less than 10% of the patients over a period of 53 months. Prospective studies comparing primary enteric drainage and bladder drainage are needed to determine the best technique, as well as immunosuppressive regimens.

Keywords: Simultaneous pancreas-kidney transplantation at the Ohio State University Medical Center.

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