Synthesis and anticonvulsant properties of some novel quinazolone-thiosemicarbazone and 4-thiazolidone derivatives.

English

el-Feky SA, Abd el-Samii ZK.

Pharmaceutical Chemistry Department, Faculty of Pharmacy, Al-Fateh University, Tripoli, Libya.

Arch Pharm (Weinheim). 1991 Jun;324(6):381-3.

Abstract

Diverse biological activities have been found in compounds having a quinazolinone ring system. A large number of 4(3H)-quinazolinones, in particular those possessing 2-alkyl-3-aryl, 2,3-dialkyl, and 2-alkyl-3-amino substitution, have been evaluated for pharmacological activity. On the other hand, thiazolidone derivatives are reported to have anesthetic, anticonvulsant, and hypnotic activity.

Keywords: Synthesis and anticonvulsant properties of some novel quinazolone-thiosemicarbazone and 4-thiazolidone derivatives.

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