The Prevalence of Microalbuminuria in type 2 Libyan Diabetics and the Efficacy of Lisinopril in its amelioration

Original article


Samira H Hussein, Issam M Hajjaji

Department of Diabetes, National Centre for Diabetes and Endocrinology

JMJ Vol.3 No.1 (March) 2004: 21-24


233 type 2 diabetics attending the outpatients’ clinic at the Diabetic Centre with a mean age of 55 years and mean duration of diabetes of 8.3 years were screened for microalbuminuria using the one-step Micral @ test on 2 separate occasions. In addition to detailed history, ECG fundoscopy and blood lipid estimations were done. BMI and waist : hip ratio were also measured. 82 (35.2 %) tested positive for microalbuminuria on 2 occasions, whilst 84 (36%) tested positive for overt proteinuria. The former were divided into 2 groups, one receiving lisinopril 20 mg/day and the other receiving placebo in a single-blind fashion. There was a significant drop in the protein excreted in the lisinopril group over a 6 months period, a drop was also noted in the placebo group, though to a much less significant level than the treatment group.

Keywords: Type 2 diabetes, microalbuminuria, lisinopril