Thyroid Disorders in Pregnancy; Management, Review and Outcomes

Original article


Mohamed Nor Azlin ¹, Zaleha Mahdy¹, Muhd Jamil ¹, Abd Wahad Norasyikin ², Kamaradin Nor Azmi ²

1-Department of Obstetric and Gynaecology, 2-Department of Medicine, Kebangsaan University Hospital, Malaysia, Jalan Yaacob Latiff, 56000 Kuala Lumpur, Malaysia

JMJ Vol.8, No.2 (Summer) 2008:114-117


Background: Thyroid disorders are not uncommon and not without complication in pregnancy. This study was done to review pregnancies complicated by thyroid disorders with respect to the management and its relation to pregnancy outcomes. Method: This was a retrospective study of 56 women who attended the combined antenatal medical clinic with thyroid disorders over a period of one year. The nature of thyroid disorders, prepregnancy counselling, thyroid hormones level, changes to treatment, postnatal evaluations and pregnancy outcomes were analysed. Results: Fifty seven percent of the patients were diagnosed hyperthyroidism and 43% with hypothyroidism. Their age range between 26 to 30 years old with 71.4% of them being multiparous. Fifty two percent booked at first trimester but only a few had prepregnancy counselling (12.5% hyperthyroid and 20.8% hypothyroid). Nearly 44% hyperthyroid and 54% hypothyroid patients had a history of subfertility. Changes in the medical treatment were mostly made in the second trimester (42%). There was one case of treated thyroid crisis with no subsequent maternal and foetal complications. Conclusion: The majority of pregnancies with thyroid disorders had good outcomes, which is made possible by the close monitoring of patients by a multidisciplinary team.

Keywords: Thyroid disorders, Pregnancy, Hyperthyroid, Hypothyroid, Thyroxin