Treatment of a Klebsiella pneumoniae KPC cellulitis and gut decolonization with ceftazidime/avibactam in a migrant from Libya



Carannante N, Pallotto C, Bernardo M, Di Caprio G, Tascini C.


J Chemother. 2018 May;30(3):183-184. doi: 10.1080/1120009X.2018.1424504. Epub 2018 Jan 16.


KPC-producing Klebsiella pneumoniae (KPC-Kp) is nowadays a global concern. Ceftazidime/avibactam is the most promising novel antibiotic combination available at the moment. We describe the case of a migrant with no risk factors for an infection due to multidrug resistant bacteria. He suffered from a KPC-Kp cellulitis and was treated with a ceftazidime/avibactam-meropenem-fosfomycin combination that not only eradicated the infection but also decontaminated his gut. Ceftazidime/avibactam-based treatment can be useful also in decontamination procedures.

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Link/DOI: 10.1080/1120009X.2018.1424504