Twenty years of renal transplantation at Ohio State University: the results of five eras of immunosuppression.

Original article


Ferguson RM, Henry ML, Elkhammas EA, Davies EA, Bumgardner GL, Pelletier RP, Rajab A.

Department of Surgery, Ohio State University College of Medicine and Public Health, Ohio State University Medical Center, 363 Means Hall,1654 Upham Dr., Columbus, OH 43210, USA.

Am J Surg. 2003 Sep;186(3):306-11.


Over the past 20 years, more than 4,000 patients have undergone an abdominal solid organ transplant at Ohio State University. The 20-year period can be divided into five eras, each defined by an immunosuppressive protocol used during that period. With each successful era came a new immunosuppressive protocol that produced an incremental improvement in outcomes of patients and graft survival resulting from the application of the newest and most sophisticated combination of immunosuppressive drugs. The incidence of acute rejection episodes and graft survival from each era are compared and demonstrate the substantial improvement in results that has been achieved over the past 20 years.

Keywords: Renal transplantation outcome; Immunosuppression