Urinary excretion of arsenic following rice consumption

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Meharg AA, Williams PN, Deacon CM, Norton GJ, Hossain M, Louhing D, Marwa E, Lawgalwi Y, Taggart M, Cascio C, Haris P.

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Environ Pollut. 2014 Nov;194:181-187. doi: 10.1016/j.envpol.2014.07.031. Epub 2014 Aug 19.

Abstract

Patterns of arsenic excretion were followed in a cohort (n = 6) eating a defined
rice diet, 300 g per day d.wt. where arsenic speciation was characterized in cooked
rice, following a period of abstinence from rice, and other high arsenic containing
foods. A control group who did not consume rice were also monitored. The rice
consumed in the study contained inorganic arsenic and dimethylarsinic acid (DMA) at
a ratio of 1:1, yet the urine speciation was dominated by DMA (90%). At steady state
(rice consumption/urinary excretion) ∼40% of rice derived arsenic was excreted via
urine. By monitoring of each urine pass throughout the day it was observed that
there was considerable variation (up to 13-fold) for an individual’s total arsenic
urine content, and that there was a time dependent variation in urinary total
arsenic content. This calls into question the robustness of routinely used first
pass/spot check urine sampling for arsenic analysis.

Keywords: .

Link/DOI: 10.1016/j.envpol.2014.07.031