Urinary excretion of arsenic following rice consumption



Meharg AA, Williams PN, Deacon CM, Norton GJ, Hossain M, Louhing D, Marwa E, Lawgalwi Y, Taggart M, Cascio C, Haris P.


Environ Pollut. 2014 Nov;194:181-187. doi: 10.1016/j.envpol.2014.07.031. Epub 2014 Aug 19.


Patterns of arsenic excretion were followed in a cohort (n = 6) eating a defined
rice diet, 300 g per day d.wt. where arsenic speciation was characterized in cooked
rice, following a period of abstinence from rice, and other high arsenic containing
foods. A control group who did not consume rice were also monitored. The rice
consumed in the study contained inorganic arsenic and dimethylarsinic acid (DMA) at
a ratio of 1:1, yet the urine speciation was dominated by DMA (90%). At steady state
(rice consumption/urinary excretion) ∼40% of rice derived arsenic was excreted via
urine. By monitoring of each urine pass throughout the day it was observed that
there was considerable variation (up to 13-fold) for an individual’s total arsenic
urine content, and that there was a time dependent variation in urinary total
arsenic content. This calls into question the robustness of routinely used first
pass/spot check urine sampling for arsenic analysis.

Keywords: .

Link/DOI: 10.1016/j.envpol.2014.07.031