Original article
English
Buzayan MM 1, Ibrahim Taher I 2
1-Bacteriology Laboratory Unit. Benghazi Center of Infectious Diseases and Immunity; 2-Department of Microbiology, Faculty of Medicine, AL-Arab Medical University, Benghazi, Libya.
Libyan J Infect Dis. 2009;3(2):19-24
Abstract
Objective: The goal of this study was to determine the frequency of urinary tract infection (UTI) among the out-patients and in-patients who are infected with human immune virus (HIV); and to compare reagent strip (nitrite) with microscopy and culture in identifying significant bacteriuria; and the effect of commonly used antibiotics on the isolated bacteria.
Methods: Three hundred and forty two urine samples were obtained from female and male adults (>12 years of age) and children (<12 years of age). Of these, 137 were inpatients admitted to Benghazi Infectious Diseases Centre and Immunity (BCIDI) and 205 outpatients during the period from June 2006 to November 2007.
Results: Of 25 positive cultures from 342 specimens (7.3%); 18 (72%) were females and 7 (28%) were males. Nitrite test, pyuria, and bacteriuria had a sensitivity of 4%; 60 %; and 12 % for detecting UTI and specificity of 100%; 91.3 % and 97.2 %, respectively. Escherichia coli was seen in 8 (32%) of cases followed by Klebsiella pneumoniae 6 (24%); Klebsiella terrigena 3 (12%); Staphylococcus aureus 3 (12%), Staphylococcus epidermidis 2 (8%), and 1 (4%) each of Staphylococcus saprophyticus; Enterobacter aerogenes; Citrobacter koseri; Proteus mirabilis. All bacterial isolates showed high resistance rates to ampicillin, nitrofurantoin, amoxicillin/clavulanic acid and Trimethoprim/sulfamethoxazole.
Conclusion: The results suggested that microscopic urinalysis or the nitrite dipstick alone can not accurately predict positive urine cultures. In view of the high resistance rates to most of the commonly used antibacterial drugs, caution must be applied when treating HIV patients infected with UTI.
Keywords: HIV, UTI, E.coli, Klebsiella spp., nitrite test, WBC, pyuria, bacteriuria
Link/DOI: