LibyaMed

The microvascular effects of insulin resistance and diabetes on cardiac structure, function, and perfusion: a cardiovascular magnetic resonance study

. . Larghat AM, Swoboda PP, Biglands JD, Kearney MT, Greenwood JP, Plein S. . Eur Heart J Cardiovasc Imaging. 2014 Dec;15(12):1368-76. doi: 10.1093/ehjci/jeu142. Epub 2014 Aug 12. Abstract AIMS: Type 2 diabetes mellitus is an independent risk factor for the development of heart failure. To better understand the mechanism by which this occurs, we …

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Tumor-infiltrating lymphocytes associate with outcome in nonendemic nasopharyngeal carcinoma: a multicenter study

. . Almangush A, Ruuskanen M, Hagström J, Hirvikoski P, Tommola S, Kosma VM, Nieminen P, Mäkitie A, Leivo I. . Hum Pathol. 2018 Nov;81:211-219. doi: 10.1016/j.humpath.2018.07.009. Epub 2018 Jul 18. Abstract The prognostic significance of tumor-infiltrating lymphocytes (TILs) has been studied recently in many cancers. For the first time in a nonendemic region, we …

Tumor-infiltrating lymphocytes associate with outcome in nonendemic nasopharyngeal carcinoma: a multicenter study Read More »

Efficacy and resistance of different artemisinin-based combination therapies: a systematic review and network meta-analysis

. . Mathenge PG, Low SK, Vuong NL, Mohamed MYF, Faraj HA, Alieldin GI, Al Khudari R, Yahia NA, Khan A, Diab OM, Mohamed YM, Zayan AH, Tawfik GM, Huy NT, Hirayama K. . Parasitol Int. 2020 Feb;74:101919. doi: 10.1016/j.parint.2019.04.016. Epub 2019 Apr 20. Abstract BACKGROUND: Malaria parasites have developed resistance to most of the …

Efficacy and resistance of different artemisinin-based combination therapies: a systematic review and network meta-analysis Read More »

Cancer Modeling-on-a-Chip with Future Artificial Intelligence Integration

. . Fetah KL, DiPardo BJ, Kongadzem EM, Tomlinson JS, Elzagheid A, Elmusrati M, Khademhosseini A, Ashammakhi N. . Small. 2019 Dec;15(50):e1901985. doi: 10.1002/smll.201901985. Epub 2019 Nov 13. Abstract Cancer is one of the leading causes of death worldwide, despite the large efforts to improve the understanding of cancer biology and development of treatments. The …

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Meningococcal and pneumococcal carriage in Hajj pilgrims: findings of a randomized controlled trial

. . Badahdah AM, Bakarman MA, Khatami A, Tashani M, Barasheed O, Alfelali M, Azeem MI, Bokhary H, Soltan O, Lahra MM, Jeoffreys N, Kok J, Dwyer DE, Booy R, Rashid H; Hajj Research Team. . J Travel Med. 2020 Jul 14;27(4):taaa032. doi: 10.1093/jtm/taaa032. Abstract BACKGROUND: Intense congestion during the Hajj pilgrimage amplifies the risk …

Meningococcal and pneumococcal carriage in Hajj pilgrims: findings of a randomized controlled trial Read More »

Machine learning in oral squamous cell carcinoma: Current status, clinical concerns and prospects for future-A systematic review

. . Alabi RO, Youssef O, Pirinen M, Elmusrati M, Mäkitie AA, Leivo I, Almangush A. . Artif Intell Med. 2021 May;115:102060. doi: 10.1016/j.artmed.2021.102060. Epub 2021 Mar 26. Abstract BACKGROUND: Oral cancer can show heterogenous patterns of behavior. For proper and effective management of oral cancer, early diagnosis and accurate prediction of prognosis are important. …

Machine learning in oral squamous cell carcinoma: Current status, clinical concerns and prospects for future-A systematic review Read More »

MeCP2 is a microsatellite binding protein that protects CA repeats from nucleosome invasion

. . Ibrahim A, Papin C, Mohideen-Abdul K, Le Gras S, Stoll I, Bronner C, Dimitrov S, Klaholz BP, Hamiche A. . Science. 2021 Jun 25;372(6549):eabd5581. doi: 10.1126/science.abd5581. Abstract The Rett syndrome protein MeCP2 was described as a methyl-CpG-binding protein, but its exact function remains unknown. Here we show that mouse MeCP2 is a microsatellite …

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Implementation research on measuring quality in primary care: balancing national needs with learning from the Eastern Mediterranean Region

. . Letaief M, Hirschhorn LR, Leatherman S, Sayed AA, Sheikh A, Siddiqi S. . Int J Qual Health Care. 2021 Aug 24;33(3):mzab119. doi: 10.1093/intqhc/mzab119. Abstract BACKGROUND: Universal Health Coverage (UHC) is a core element of ensuring healthy lives, marking the third Sustainable Development Goal. It requires providing quality primary health-care (PHC) services. Assessment of …

Implementation research on measuring quality in primary care: balancing national needs with learning from the Eastern Mediterranean Region Read More »

Long-Term Iron Deficiency and Dietary Iron Excess Exacerbate Acute Dextran Sodium Sulphate-Induced Colitis and Are Associated with Significant Dysbiosis

. . Mahalhal A, Burkitt MD, Duckworth CA, Hold GL, Campbell BJ, Pritchard DM, Probert CS. . Int J Mol Sci. 2021 Mar 31;22(7):3646. doi: 10.3390/ijms22073646. Abstract BACKGROUND: Oral iron supplementation causes gastrointestinal side effects. Short-term alterations in dietary iron exacerbate inflammation and alter the gut microbiota, in murine models of colitis. Patients typically take …

Long-Term Iron Deficiency and Dietary Iron Excess Exacerbate Acute Dextran Sodium Sulphate-Induced Colitis and Are Associated with Significant Dysbiosis Read More »