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. . Elseragy A, Salo T, Coletta RD, Kowalski LP, Haglund C, Nieminen P, Mäkitie AA, Leivo I, Almangush A. . Am J Surg Pathol. 2019 May;43(5):703-709. doi: 10.1097/PAS.0000000000001241. Abstract The World Health Organization (WHO) grading system has a low prognostic value for early-stage oral tongue squamous cell carcinoma; greater prognostic power has been shown …

A Proposal to Revise the Histopathologic Grading System of Early Oral Tongue Cancer Incorporating Tumor Budding Read More »

. . Pujol-Navarro N, Al Qaraghuli MM, Kubiak-Ossowska K, Alsaadi MM, Horne GA, Soutar RL, Paspali E, Ferro VA, Williams MT, Mulheran PA. . Ther Deliv. 2021 Sep 27. doi: 10.4155/tde-2021-0041. Online ahead of print. Abstract Multiple myeloma is the second most common hematological malignancy in adults, accounting for 2% of all cancer-related deaths in …

Multiple myeloma: therapeutic delivery of antibodies and aptamers Read More »

. . Almangush A, Alabi RO, Troiano G, Coletta RD, Salo T, Pirinen M, Mäkitie AA, Leivo I. . BMC Cancer. 2021 Apr 30;21(1):480. doi: 10.1186/s12885-021-08222-8. Abstract BACKGROUND: The clinical significance of tumor-stroma ratio (TSR) has been examined in many tumors. Here we systematically reviewed all studies that evaluated TSR in head and neck cancer. …

Clinical significance of tumor-stroma ratio in head and neck cancer: a systematic review and meta-analysis Read More »

. . Heikkinen I, Bello IO, Wahab A, Hagström J, Haglund C, Coletta RD, Nieminen P, Mäkitie AA, Salo T, Leivo I, Almangush A. . Am J Surg Pathol. 2019 Oct;43(10):1392-1396. doi: 10.1097/PAS.0000000000001323. Abstract BACKGROUND: Vaccination and single-dose rifampin are the main proven effective intervention types for preventing leprosy among contacts of Mycobacterium leprae endemic …

Assessment of Tumor-infiltrating Lymphocytes Predicts the Behavior of Early-stage Oral Tongue Cancer Read More »

. . Almangush A, Mäkitie AA, Triantafyllou A, de Bree R, Strojan P, Rinaldo A, Hernandez-Prera JC, Suárez C, Kowalski LP, Ferlito A, Leivo I. . Oral Oncol. 2020 Aug;107:104799. doi: 10.1016/j.oraloncology.2020.104799. Epub 2020 May 20. Abstract Metabolomics coupled with heavy-atom isotope-labelled glucose has been used to probe the metabolic pathways active in cultured bloodstream …

Staging and grading of oral squamous cell carcinoma: An update Read More »

. . Katwan OJ, Alghamdi F, Almabrouk TA, Mancini SJ, Kennedy S, Oakhill JS, Scott JW, Salt IP. . Biochem J. 2019 Jun 26;476(12):1725-1740. doi: 10.1042/BCJ20180714. Abstract BACKGROUND: Skeletal imaging techniques have become clinically valuable methods for measuring and assessing bone mineral density in children and young people. Dual-energy X-ray absorptiometry (DXA) is the current …

AMP-activated protein kinase complexes containing the β2 regulatory subunit are up-regulated during and contribute to adipogenesis Read More »

. . Wiener P, Robert C, Ahbara A, Salavati M, Abebe A, Kebede A, Wragg D, Friedrich J, Vasoya D, Hume DA, Djikeng A, Watson M, Prendergast JGD, Hanotte O, Mwacharo JM, Clark EL. . Genome Biol Evol. 2021 Mar 1;13(3):evab014. doi: 10.1093/gbe/evab014. Abstract Great progress has been made over recent years in the identification …

Whole-Genome Sequence Data Suggest Environmental Adaptation of Ethiopian Sheep Populations Read More »

. . Hajjaji IM, Eshwihdi N, Barrowman N. . Int J Clin Pract. 2019 Jun;73(6):e13348. doi: 10.1111/ijcp.13348. Epub 2019 Apr 29. Abstract AIM OF THE STUDY: To test if changing the Iftar insulin to a 50:50 mixed analog insulin from a 30:70 human insulin at the same total dose leads to improvement in the postprandial …

Comparison of analog insulin mix 50:50 with human insulin mix 30:70 in persons with type 2 diabetes during Ramadan Read More »

. . Creek DJ, Mazet M, Achcar F, Anderson J, Kim DH, Kamour R, Morand P, Millerioux Y, Biran M, Kerkhoven EJ, Chokkathukalam A, Weidt SK, Burgess KE, Breitling R, Watson DG, Bringaud F, Barrett MP. . PLoS Pathog. 2015 Mar 16;11(3):e1004689. doi: 10.1371/journal.ppat.1004689. 2015 Mar. Abstract The burden of depression and other mental disorders …

Probing the metabolic network in bloodstream-form Trypanosoma brucei using untargeted metabolomics with stable isotope labelled glucose Read More »

. . Sayed IM, Hammam ARA, Elfaruk MS, Alsaleem KA, Gaber MA, Ezzat AA, Salama EH, Elkhawaga AA, El-Mokhtar MA. . Microorganisms. 2020 Aug 12;8(8):1231. doi: 10.3390/microorganisms8081231. Abstract Hepatitis E virus (HEV) infection is endemic in developing and developed countries. HEV was reported to be excreted in the milk of ruminants, raising the possibility of …

Enhancement of the Molecular and Serological Assessment of Hepatitis E Virus in Milk Samples Read More »