LibyaMed

Formulation and Bioavailability of Novel Mucoadhesive Buccal Films for Candesartan Cilexetil in Rats

. . Mady OY, Abulmeaty MMA, Donia AA, Al-Khureif AA, Al-Shoubki AA, Abudawood M, Abdel Moety DA. . Membranes (Basel). 2021 Aug 26;11(9):659. doi: 10.3390/membranes11090659. Abstract BACKGROUND AND AIM: Ovine theileriosis caused by Theileria ovis and Theileria lestoquardi is an important infectious disease affecting small ruminants in regions of the tropic and subtropic zones. There …

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Rationale and design of the Pan-African Sudden Cardiac Death survey: the Pan-African SCD study

. . Bonny A, Ngantcha M, Amougou SN, Kane A, Marrakchi S, Okello E, Taty G, Gehani A, Diakite M, Talle M, Lambiase P, Houenassi M, Chin A, Otieno H, Temu G, Owusu IK, Karaye KM, Awad AA, Winkel BG, Priori SG; Pan‐African Society of Cardiology (PASCAR) Task Force on Sudden Cardiac Death. . Cardiovasc …

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C. elegans and mutants with chronic nicotine exposure as a novel model of cancer phenotype

. . Kanteti R, Dhanasingh I, El-Hashani E, Riehm JJ, Stricker T, Nagy S, Zaborin A, Zaborina O, Biron D, Alverdy JC, Im HK, Siddiqui S, Padilla PA, Salgia R. . Cancer Biol Ther. 2016;17(1):91-103. doi: 10.1080/15384047.2015.1108495. Abstract We previously investigated MET and its oncogenic mutants relevant to lung cancer in C. elegans. The inactive …

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Biological roles of KGF, CTGF and TGF-β in cyclosporine-A- and phenytoin- induced gingival overgrowth: A comparative experimental animal study

. . Al-Hamilly NS, Radwan LR, Abdul-Rahman M, Mourad MI, Grawish ME. . Arch Oral Biol. 2016 Jun;66:38-43. doi: 10.1016/j.archoralbio.2016.02.006. Epub 2016 Feb 11. Abstract OBJECTIVE: To identify the possible biological roles of keratinocyte growth factor (KGF), connective tissue growth factor (CTGF) and transforming growth factor-β (TGF-β) in cyclosporine-A (CsA) and phenytoin (PNT)-induced gingival overgrowth …

Biological roles of KGF, CTGF and TGF-β in cyclosporine-A- and phenytoin- induced gingival overgrowth: A comparative experimental animal study Read More »

Adalimumab ameliorates OVA-induced airway inflammation in mice: Role of CD4(+) CD25(+) FOXP3(+) regulatory T-cells

. . Elsakkar MG, Sharaki OA, Abdallah DM, Mostafa DK, Shekondali FT. . Eur J Pharmacol. 2016 Sep 5;786:100-108. doi: 10.1016/j.ejphar.2016.06.002. Epub 2016 Jun 2. Abstract Asthma is a chronic inflammatory heterogeneous disorder initiated by a dysregulated immune response which drives disease development in susceptible individuals. Though T helper 2 (TH2) biased responses are usually …

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Enhanced glutamine uptake influences composition of immune cell infiltrates in breast cancer

. . Ansari RE, Craze ML, Althobiti M, Alfarsi L, Ellis IO, Rakha EA, Green AR. . Br J Cancer. 2020 Jan;122(1):94-101. doi: 10.1038/s41416-019-0626-z. Epub 2019 Dec 10. Abstract BACKGROUND: Cancer cells must alter their metabolism to support proliferation. Immune evasion also plays a role in supporting tumour progression. This study aimed to find whether …

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The solute carrier SLC7A8 is a marker of favourable prognosis in ER-positive low proliferative invasive breast cancer

. . El Ansari R, Alfarsi L, Craze ML, Masisi BK, Ellis IO, Rakha EA, Green AR. . Breast Cancer Res Treat. 2020 May;181(1):1-12. doi: 10.1007/s10549-020-05586-6. Epub 2020 Mar 21. Abstract PURPOSE: Breast cancer (BC) is a heterogeneous disease consisting of various subtypes, with different prognostic and therapeutic outcomes. The amino acid transporter, SLC7A8, is …

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Risk stratification in oral squamous cell carcinoma using staging of the eighth American Joint Committee on Cancer: Systematic review and meta-analysis

. . Almangush A, Pirinen M, Youssef O, Mäkitie AA, Leivo I. . Head Neck. 2020 Oct;42(10):3002-3017. doi: 10.1002/hed.26344. Epub 2020 Jun 17. Abstract The eighth edition of the American Joint Committee on Cancer (AJCC8) staging manual has major changes in oral squamous cell carcinoma (OSCC). We searched PubMed, OvidMedline, Scopus, and Web of Science …

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Elderly patients have increased perioperative morbidity and mortality from oesophagectomy for oesophageal cancer: A systematic review and meta-analysis

. . Kamarajah SK, Gujjuri RR, Elhadi M, Umar H, Bundred JR, Subramanya MS, Evans RP, Powell SL, Griffiths EA. . Eur J Surg Oncol. 2021 Aug;47(8):1828-1835. doi: 10.1016/j.ejso.2021.02.030. Epub 2021 Mar 27. Abstract BACKGROUND: Although oesophagectomy remains technically challenging and associated with high morbidity and mortality, it is now increasingly performed in an ever-ageing …

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Mechanical Performance of Reclaimed Asphalt Pavement Modified with Waste Frying Oil and Crumb Rubber

. . Bilema M, Aman MY, Hassan NA, Memon ZA, Omar HA, Yusoff NIM, Milad A. . Materials (Basel). 2021 May 24;14(11):2781. doi: 10.3390/ma14112781. Abstract Researchers are exploring the utilisation of reclaimed asphalt pavement (RAP) as a recycled material to determine the performance of non-renewable natural aggregates and other road products such as asphalt binder, …

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