LibyaMed

Cost-effectiveness of Humanitarian Pediatric Cardiac Surgery Programs in Low- and Middle-Income Countries

. . Cardarelli M, Vaikunth S, Mills K, DiSessa T, Molloy F, Sauter E, Bowtell K, Rivera R, Shin AY, Novick W. . JAMA Netw Open. 2018 Nov 2;1(7):e184707. doi: 10.1001/jamanetworkopen.2018.4707. Abstract IMPORTANCE: Endorsement of global humanitarian interventions is based on either proven cost-effectiveness or perceived public health benefits. The cost-effectiveness and long-term benefits of …

Cost-effectiveness of Humanitarian Pediatric Cardiac Surgery Programs in Low- and Middle-Income Countries Read More »

Project ECHO: a Potential Best-Practice Tool for Training Healthcare Providers in Oral Cancer Screening and Tobacco Cessation

. . Nethan ST, Hariprasad R, Babu R, Kumar V, Sharma S, Mehrotra R. . J Cancer Educ. 2020 Oct;35(5):965-971. doi: 10.1007/s13187-019-01549-8. Abstract The oral cancer pandemic and inadvertent tobacco consumption have rendered timely oral cavity screening and tobacco cessation essential, skills which most healthcare providers (HCPs) lack. Project “Extension for Community Healthcare Outcomes” (ECHO) …

Project ECHO: a Potential Best-Practice Tool for Training Healthcare Providers in Oral Cancer Screening and Tobacco Cessation Read More »

Random insertion and gene disruption via transposon mutagenesis of Ureaplasma parvum using a mini-transposon plasmid

. . Aboklaish AF, Dordet-Frisoni E, Citti C, Toleman MA, Glass JI, Spiller OB. . Int J Med Microbiol. 2014 Nov;304(8):1218-25. doi: 10.1016/j.ijmm.2014.09.003. Epub 2014 Sep 26. Abstract While transposon mutagenesis has been successfully used for Mycoplasma spp. to disrupt and determine non-essential genes, previous attempts with Ureaplasma spp. have been unsuccessful. Using a polyethylene …

Random insertion and gene disruption via transposon mutagenesis of Ureaplasma parvum using a mini-transposon plasmid Read More »

Polyphenols Modulating Effects of PD-L1/PD-1 Checkpoint and EMT-Mediated PD-L1 Overexpression in Breast Cancer

. . Messeha SS, Zarmouh NO, Soliman KFA. . Nutrients. 2021 May 19;13(5):1718. doi: 10.3390/nu13051718. Abstract Investigating dietary polyphenolic compounds as antitumor agents are rising due to the growing evidence of the close association between immunity and cancer. Cancer cells elude immune surveillance for enhancing their progression and metastasis utilizing various mechanisms. These mechanisms include …

Polyphenols Modulating Effects of PD-L1/PD-1 Checkpoint and EMT-Mediated PD-L1 Overexpression in Breast Cancer Read More »

Acute coronary syndrome in immigrants and non-immigrants : Results of an Austrian prospective pilot study

. . Gündüz D, Lesjak A, Wiedemann A, Avanzini M, Winkler WB, Ucar-Altenberger H, Stöllberger C, Weidinger F. . Wien Klin Wochenschr. 2017 Dec;129(23-24):900-905. doi: 10.1007/s00508-017-1279-7. Epub 2017 Oct 20. Abstract BACKGROUND: There are indications that immigrant patients with acute coronary syndrome (ACS) differ in demographic characteristics and clinical presentation from non-immigrant patients. The aim …

Acute coronary syndrome in immigrants and non-immigrants : Results of an Austrian prospective pilot study Read More »

Continued 26S proteasome dysfunction in mouse brain cortical neurons impairs autophagy and the Keap1-Nrf2 oxidative defence pathway

. . Ugun-Klusek A, Tatham MH, Elkharaz J, Constantin-Teodosiu D, Lawler K, Mohamed H, Paine SM, Anderson G, John Mayer R, Lowe J, Ellen Billett E, Bedford L. . Cell Death Dis. 2017 Jan 5;8(1):e2531. doi: 10.1038/cddis.2016.443. Abstract The ubiquitin-proteasome system (UPS) and macroautophagy (autophagy) are central to normal proteostasis and interdependent in that autophagy …

Continued 26S proteasome dysfunction in mouse brain cortical neurons impairs autophagy and the Keap1-Nrf2 oxidative defence pathway Read More »

Detection and Molecular Characterization of Foot and Mouth Disease Viruses from Outbreaks in Some States of Northern Nigeria 2013-2015

. . Ehizibolo DO, Haegeman A, De Vleeschauwer AR, Umoh JU, Kazeem HM, Okolocha EC, Van Borm S, De Clercq K. . Transbound Emerg Dis. 2017 Dec;64(6):1979-1990. doi: 10.1111/tbed.12602. Epub 2017 Jan 17. Abstract Control measures for foot and mouth disease (FMD) in Nigeria have not been implemented due to the absence of locally produced …

Detection and Molecular Characterization of Foot and Mouth Disease Viruses from Outbreaks in Some States of Northern Nigeria 2013-2015 Read More »

Disparities in pregnancy-related deaths: spatial and Bayesian network analyses of maternal mortality ratio in 54 African countries

. . Yaya S, Anjorin SS, Adedini SA. . BMJ Glob Health. 2021 Feb;6(2):e004233. doi: 10.1136/bmjgh-2020-004233. Abstract BACKGROUND: Maternal mortality remains a public health problem despite several global efforts. Globally, about 830 women die of pregnancy-related death per day, with more than two-third of these cases occurring in Africa. We examined the spatial distribution of …

Disparities in pregnancy-related deaths: spatial and Bayesian network analyses of maternal mortality ratio in 54 African countries Read More »

Non-antibacterial tetracycline formulations: host-modulators in the treatment of periodontitis and relevant systemic diseases

. . Golub LM, Elburki MS, Walker C, Ryan M, Sorsa T, Tenenbaum H, Goldberg M, Wolff M, Gu Y. . Int Dent J. 2016 Jun;66(3):127-35. doi: 10.1111/idj.12221. Epub 2016 Mar 23. Abstract Traditionally, the dental profession has primarily treated periodontitis using a mechanical/surgical, rather than a pharmaceutical, approach. However, based on experiments several decades …

Non-antibacterial tetracycline formulations: host-modulators in the treatment of periodontitis and relevant systemic diseases Read More »