LibyaMed

Comparison of CD44 expression in primary tumours and metastases of colorectal cancer.

Original article English Bendardaf R, Algars A, Elzagheid A, Korkeila E, Ristamaki R, Lamlum H, Collan Y, Syrjanen K, Pyrhonen S. Department of Oncology and Radiotherapy, Turku University Hospital, Turku, Finland. riyben@utu.fi Oncol Rep. 2006 Oct;16(4):741-6. Abstract A better understanding on the development of a metastatic phenotype in colorectal cancer (CRC) is essential to help …

Comparison of CD44 expression in primary tumours and metastases of colorectal cancer. Read More »

E-cadherin expression pattern in primary colorectal carcinomas and their metastases reflects disease outcome.

Original article English Elzagheid A, Algars A, Bendardaf R, Lamlum H, Ristamaki R, Collan Y, Syrjanen K, Pyrhonen S. Department of Oncology and Radiotherapy, Turku University Hospital, Savitehtaankatu 1 PB 52, FIN-20520 Turku, Finland. adibel@utu.fi World J Gastroenterology. 2006 Jul 21;12(27):4304-9. Abstract AIM: To investigate the changes that occur in E-cadherin expression during the process …

E-cadherin expression pattern in primary colorectal carcinomas and their metastases reflects disease outcome. Read More »

Thymidylate synthase expression levels: a prognostic and predictive role in advanced colorectal cancer.

Original article English Bendardaf R, Lamlum H, Elzagheid A, Ristamaki R, Pyrhonen S. Department of Oncology and Radiotherapy, Turku University Hospital, Savitehtaankatu 1, PB 52, FIN-20521 Turku, Finland. riyben@utu.fi Oncol Rep. 2005 Sep;14(3):657-62. Abstract Thymidylate synthase (TS) is the rate-limiting enzyme in the synthesis of pyrimidine nucleotides, required for DNA synthesis, and is also a …

Thymidylate synthase expression levels: a prognostic and predictive role in advanced colorectal cancer. Read More »

E-cadherin, CD44s and CD44v6 correlate with tumour differentiation in colorectal cancer.

Original article English Bendardaf R, Elzagheid A, Lamlum H, Ristamaki R, Collan Y, Pyrhonen S. Department of Oncology and Radiotherapy, Turku University Hospital, Turku, Finland. riyben@utu.fi Oncol Rep. 2005 May;13(5):831-5. Abstract Cell adhesion molecules (CAMs) are cell surface glycoproteins that are important in cell-cell and cell-matrix interactions and play an important role in cell growth …

E-cadherin, CD44s and CD44v6 correlate with tumour differentiation in colorectal cancer. Read More »

Prognostic and predictive molecular markers in colorectal carcinoma.

Original article English Bendardaf R, Lamlum H, Pyrhonen S. Department of Oncology and Radiotherapy, Turku University Central Hospital, Kiinamyllynkatu 10, FIN-20520, Turku, Finland. riyben@utu.fi Anticancer Res. 2004 Jul-Aug;24(4):2519-30. Abstract Tumour markers are molecules occurring in blood or tissue that are associated with cancer and whose measurement or identification is useful in patient diagnosis or clinical …

Prognostic and predictive molecular markers in colorectal carcinoma. Read More »

Response to chemotherapy (irinotecan plus 5-fluorouracil) in colorectal carcinoma can be predicted by tumour DNA content.

Original article English Bendardaf R, Lamlum H, Ristamaki R, Algars A, Collan Y, Pyrhonen S. Department of Oncology and Radiotherapy, Turku University Central Hospital, Turku, Finland. Oncology. 2004;66(1):46-52. Abstract OBJECTIVE: The aim of this study was to identify markers that might predict response to chemotherapy. Postoperative chemotherapy improves the outcome in stage III colon cancer …

Response to chemotherapy (irinotecan plus 5-fluorouracil) in colorectal carcinoma can be predicted by tumour DNA content. Read More »

Multiple spuriously abnormal thyroid function indices due to heterophilic antibodies.

Case report English Fiad TM, Duffy J, McKenna TJ. Department of Endocrinology, St Vincent’s Hospital, Dublin, Ireland. Clin Endocrinol (Oxf). 1994 Sep;41(3):391-5. Abstract A 57-year-old man with a history of liver fibrosis, portal hypertension and hypersplenism had thyroid function assessed because of weight loss. Free T4 (FT4), total T4 (TT4), total T3 (TT3) and TSH …

Multiple spuriously abnormal thyroid function indices due to heterophilic antibodies. Read More »

Premixed insulin preparations in pen syringes maintain glycemic control and are preferred by patients.

Original article English Dunbar JM, Madden PM, Gleeson DT, Fiad TM, McKenna TJ. Diabetes Centre, St. Vincent’s Hospital, Elm Park, Dublin, Ireland. Diabetes Care. 1994 Aug;17(8):874-8. Abstract OBJECTIVE–To examine the impact on glycemic control of substituting a range of premixed insulins for the standard treatment with patient-mixed insulin combinations. In addition, a pen-type syringe was …

Premixed insulin preparations in pen syringes maintain glycemic control and are preferred by patients. Read More »

The overnight single-dose metyrapone test is a simple and reliable index of the hypothalamic-pituitary-adrenal axis.

Original article English Fiad TM, Kirby JM, Cunningham SK, McKenna TJ. Department of Endocrinology and Diabetes Mellitus, St Vincent’s Hospital, Dublin, Ireland. Clin Endocrinol (Oxf). 1994 May;40(5):603-9. Abstract OBJECTIVE: The ACTH stimulation test examines adrenal responsiveness but may not examine the entire hypothalamic-pituitary-adrenal (HPA) axis and requires parenteral administration. The cortisol response to hypoglycaemia provides …

The overnight single-dose metyrapone test is a simple and reliable index of the hypothalamic-pituitary-adrenal axis. Read More »

The prevalence of microalbuminuria and associated risk factors in a population with insulin-dependent diabetes mellitus.

Original article English Fiad TM, Freaney R, Murray B, McKenna MJ. Department of Endocrinology and Diabetes, St. Vincent’s Hospital, Dublin. Ir J Med Sci. 1993 Aug;162(8):318-20. Abstract The prevalence of microalbuminuria was studied in a clinic population of patients with insulin-dependent diabetes mellitus [IDDM] with disease duration longer than 5 years. 75 patients were included …

The prevalence of microalbuminuria and associated risk factors in a population with insulin-dependent diabetes mellitus. Read More »