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The prevalence of microalbuminuria and associated risk factors in a population with insulin-dependent diabetes mellitus.

Original article English Fiad TM, Freaney R, Murray B, McKenna MJ. Department of Endocrinology and Diabetes, St. Vincent’s Hospital, Dublin. Ir J Med Sci. 1993 Aug;162(8):318-20. Abstract The prevalence of microalbuminuria was studied in a clinic population of patients with insulin-dependent diabetes mellitus [IDDM] with disease duration longer than 5 years. 75 patients were included …

The prevalence of microalbuminuria and associated risk factors in a population with insulin-dependent diabetes mellitus. Read More »

The overnight single-dose metyrapone test is a simple and reliable index of the hypothalamic-pituitary-adrenal axis.

Original article English Fiad TM, Kirby JM, Cunningham SK, McKenna TJ. Department of Endocrinology and Diabetes Mellitus, St Vincent’s Hospital, Dublin, Ireland. Clin Endocrinol (Oxf). 1994 May;40(5):603-9. Abstract OBJECTIVE: The ACTH stimulation test examines adrenal responsiveness but may not examine the entire hypothalamic-pituitary-adrenal (HPA) axis and requires parenteral administration. The cortisol response to hypoglycaemia provides …

The overnight single-dose metyrapone test is a simple and reliable index of the hypothalamic-pituitary-adrenal axis. Read More »

Premixed insulin preparations in pen syringes maintain glycemic control and are preferred by patients.

Original article English Dunbar JM, Madden PM, Gleeson DT, Fiad TM, McKenna TJ. Diabetes Centre, St. Vincent’s Hospital, Elm Park, Dublin, Ireland. Diabetes Care. 1994 Aug;17(8):874-8. Abstract OBJECTIVE–To examine the impact on glycemic control of substituting a range of premixed insulins for the standard treatment with patient-mixed insulin combinations. In addition, a pen-type syringe was …

Premixed insulin preparations in pen syringes maintain glycemic control and are preferred by patients. Read More »

Multiple spuriously abnormal thyroid function indices due to heterophilic antibodies.

Case report English Fiad TM, Duffy J, McKenna TJ. Department of Endocrinology, St Vincent’s Hospital, Dublin, Ireland. Clin Endocrinol (Oxf). 1994 Sep;41(3):391-5. Abstract A 57-year-old man with a history of liver fibrosis, portal hypertension and hypersplenism had thyroid function assessed because of weight loss. Free T4 (FT4), total T4 (TT4), total T3 (TT3) and TSH …

Multiple spuriously abnormal thyroid function indices due to heterophilic antibodies. Read More »

Role of progesterone deficiency in the development of luteinizing hormone and androgen abnormalities in polycystic ovary syndrome.

Original article English Fiad TM, Cunningham SK, McKenna TJ. Department of Investigative Endocrinology St Vincent’s Hospital, Dublin, Ireland. Eur J Endocrinol. 1996 Sep;135(3):335-9. Abstract The aetiology of polycystic ovary syndrome (PCOS) is unknown. It is uniquely characterized by oligomenorrhoea or amenorrhoea associated with normal or high oestrogen levels. This prospective clinical study was designed to …

Role of progesterone deficiency in the development of luteinizing hormone and androgen abnormalities in polycystic ovary syndrome. Read More »

Effects of nifedipine treatment on the renin-angiotensin-aldosterone axis.

Original article English Fiad TM, Cunningham SK, Hayes FJ, McKenna TJ. Department of Investigative Endocrinology, University College Dublin, Ireland. J Clin Endocrinol Metab. 1997 Feb;82(2):457-60. Abstract Nifedipine is a commonly used agent in treating hypertension and angina because of its vasodilator properties. An inhibitory role of nifedipine on aldosterone (Aldo) biosynthesis has been documented in …

Effects of nifedipine treatment on the renin-angiotensin-aldosterone axis. Read More »

Decline in insulin-like growth factor I levels after clomiphene citrate does not correct hyperandrogenemia in polycystic ovary syndrome.

Original article English Fiad TM, Smith TP, Cunningham SK, McKenna TJ. Department of Investigative Endocrinology, University College, Dublin, Ireland. J Clin Endocrinol Metab. 1998 Jul;83(7):2394-8. Abstract It is widely accepted that the action of clomiphene citrate (CC) is mediated through its antiestrogenic properties on the hypothalamic-pituitary axis. Although insulin-like growth factor I (IGF-I) enhances the …

Decline in insulin-like growth factor I levels after clomiphene citrate does not correct hyperandrogenemia in polycystic ovary syndrome. Read More »

Hyperprolactinaemia: analysis of presentation, diagnosis and treatment in the endocrine service of a general hospital.

Original article English Suliman AM, al-saber F, Hayes F, Fiad T, Culliton M, Cunningham S, McKenna TJ. Dept. of Endocrinology and Diabetes Mellitus, St. Vincent’s Hospital, Elm Park, Dublin. Ir Med J. 2000 May;93(3):74-6. Abstract The charts of 184 patients with clinically significant hyperprolactinaemia who presented to a teaching hospital between 1978-1995 were reviewed, 158 …

Hyperprolactinaemia: analysis of presentation, diagnosis and treatment in the endocrine service of a general hospital. Read More »