. . Mohamed SS, Tamer AR, Bensaber SM, Jaeda MI, Ermeli NB, Allafi AA, Mrema IA, Erhuma M, Hermann A, Gbaj AM. . Naunyn Schmiedebergs Arch Pharmacol. 2013 Sep;386(9):813-22. doi: 10.1007/s00210-013-0883-y. Epub 2013 May 26. Abstract A series of sulfanilamide Schiff base derivatives (1 to 15) have been designed as potential antitubulin agents depending on …
. . Chandu BR, Kanala K, Hwisa NT, Katakam P, Khagga M. . Springerplus. 2013 Apr 30;2(1):194. doi: 10.1186/2193-1801-2-194. Print 2013 Dec. Abstract A bioequivalence study was proved of generic Febuxostat 80 mg tablets (T) in healthy volunteers.For this purpose, Authors developed a simple, sensitive, selective, rapid, rugged and reproducible liquid chromatography-tandem mass spectrometry method …
. . Azam F, Abugrain IM, Sanalla MH, Elnaas RF, Rajab IA. . Bioinformation. 2013 Oct 16;9(17):864-9. doi: 10.6026/97320630009864. 2013. Abstract Glutamate receptors have been implicated in various neurological disorders and their antagonism offers a suitable approach for the treatment of such disorders. The field of drug design and discovery aims to find best medicines …
. . Chaabane A, Neifar L, Justine JL. . Parasite. 2015;22:9. doi: 10.1051/parasite/2015005. Epub 2015 Feb 13. Abstract Pseudorhabdosynochus regius n. sp. is described from the gills of the mottled grouper Mycteroperca rubra caught off Senegal, Tunisia and Libya (type-locality: off Dakar, Senegal). The species is distinguished from its congeners by the structure of its …
. . Tabal S, Elbanani A, Deyab M, Abulayha A. . Cancer Biother Radiopharm. 2015 Apr;30(3):125-31. doi: 10.1089/cbr.2014.1769. Epub 2015 Feb 25. Abstract In the treatment of B cell non-Hodgkin’s lymphoma, rituximab is used in combination with different chemotherapeutics to improve its efficacy, but the mechanisms involved are not fully understood. The authors examined the …
. . Chinnasamy S, Chinnasamy S, Muthusamy K. . J Recept Signal Transduct Res. 2016;36(2):111-8. doi: 10.3109/10799893.2015.1056306. Epub 2015 Sep 30. Abstract Phospholipase A2 (PLA2) is the most abundant protein found in snake venom. PLA2 induces a variety of pharmacological effects such as neurotoxicity, myotoxicity and cardiotoxicity as well as anticoagulant, hemolytic, anti-platelet, hypertensive, hemorrhagic …
High-affinity selective inhibitor against phospholipase A2 (PLA2): a computational study Read More »
. . Ahmed M, Rghigh A. . Curr Clin Pharmacol. 2016;11(3):191-210. doi: 10.2174/1574884711666160701000900. Abstract Endothelin-1, (ET-1, EDN1) is an endogenous polypeptide which demonstrates dominant vasoconstriction activity and mitogenic effect. It has positive inotropic and chronotropic effects on the heart, stimulates the sympathetic and the renin-angiotensin-aldosterone systems and modifies homeostasis. The human ET-1 gene which consists …
. . Musaiger AO, Al-Mannai M, Al-Haifi AR, Nabag F, Elati J, Abahussain N, Tayyem R, Jalambo M, Benhamad M, Al-Mufty B. . Nutr Hosp. 2016 Sep 20;33(5):567. doi: 10.20960/nh.567. Abstract OBJECTIVE: The aim of this study was to highlight the prevalence of overweight and obesity among adolescents in eight Arab countries. METHODS: A school-based …
. . Abiedalla Y, DeRuiter J, Clark CR. . J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Mar 24;1048:38-48. doi: 10.1016/j.jchromb.2017.01.045. Epub 2017 Feb 7. Abstract The desoxy phenethylamine analogues in this study represent a combination of alkyl side-chain and cyclic amines (azetidine, pyrrolidine, piperidine and azepane) to yield a set of molecules of …
. . Alsonosi AM, Holy O, Forsythe SJ. . Antonie Van Leeuwenhoek. 2019 Mar;112(3):435-450. doi: 10.1007/s10482-018-1178-6. Epub 2018 Oct 12. Abstract Cronobacter malonaticus is a member of the genus Cronobacter which is considered an opportunistic pathogen. The significance of C. malonaticus has recently increased since it was documented to be involved in several serious neonatal …