LibyaMed

“Do We Know Jack” About JAK? A Closer Look at JAK/STAT Signaling Pathway

. . Bousoik E, Montazeri Aliabadi H. . Front Oncol. 2018 Jul 31;8:287. doi: 10.3389/fonc.2018.00287. 2018. Abstract Janus tyrosine kinase (JAK) family of proteins have been identified as crucial proteins in signal transduction initiated by a wide range of membrane receptors. Among the proteins in this family JAK2 has been associated with important downstream proteins, …

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Translational Significance of Selective Estrogen Receptor Modulators in Psychiatric Disorders

. . Khan MM. . Int J Endocrinol. 2018 Oct 8;2018:9516592. doi: 10.1155/2018/9516592. 2018. Abstract Accumulating data from various clinical trial studies suggests that adjuvant therapy with ovarian hormones (estrogens) could be effective in reducing cognitive deficit and psychopathological symptoms in women with psychiatric disorders. However, estrogen therapy poses serious limitations and health issues including …

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A medical mystery of complex regional pain syndrome

. . Eldufani J, Elahmer N, Blaise G. . Heliyon. 2020 Feb 19;6(2):e03329. doi: 10.1016/j.heliyon.2020.e03329. 2020 Feb. Abstract Complex regional pain syndrome (CRPS) is a condition of neuropathic pain, which is characterized by significant autonomic and inflammatory features. CRPS occurs in patients who have limb surgery, limb fractures, or trauma. Many patients may have pain …

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Integration of sexual and reproductive health services in the provision of primary health care in the Arab States: status and a way forward

. . Kabakian-Khasholian T, Quezada-Yamamoto H, Ali A, Sahbani S, Afifi M, Rawaf S, El Rabbat M. . Sex Reprod Health Matters. 2020 Dec;28(2):1773693. doi: 10.1080/26410397.2020.1773693. Abstract Different approaches are used for integration of sexual and reproductive health (SRH) services at the primary health care (PHC) level, aiming at providing comprehensive services leaving no one …

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The Antioxidant Role of a Taurine-Enriched Diet in Combating the Immunotoxic and Inflammatory Effects of Pyrethroids and/or Carbamates in Oreochromis niloticus

. . Abdel-Rahman Mohamed A, Abdel Rahman AN, Salem GA, Deib MME, Nassan MA, Rhouma NR, Khater SI. . Animals (Basel). 2021 May 5;11(5):1318. doi: 10.3390/ani11051318. Abstract Indiscriminate use of insecticides is a major concern due to its ubiquitous occurrence and potential toxicity to aquatic animals. This study investigated the adverse effects of lambda-cyhalothrin (LCT; …

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Status of HIV and hepatitis C virus infections among prisoners in the Middle East and North Africa: review and synthesis

. . Heijnen M, Mumtaz GR, Abu-Raddad LJ. . J Int AIDS Soc. 2016 May 27;19(1):20873. doi: 10.7448/IAS.19.1.20873. 2016. Abstract INTRODUCTION: The status of HIV and hepatitis C virus (HCV) infections among incarcerated populations in the Middle East and North Africa (MENA) and the links between prisons and the HIV epidemic are poorly understood. This …

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Adsorption, kinetic and thermodynamic studies for manganese extraction from aqueous medium using mesoporous silica

. . Idris SA. . J Colloid Interface Sci. 2015 Feb 15;440:84-90. doi: 10.1016/j.jcis.2014.10.022. Epub 2014 Oct 29. Abstract This paper describes studies of functionalized mesoporous silica employed as adsorbent for Mn(II) from aqueous solutions. The surface area of MCM-41 and diethylenetriamine functionalized-MCM-41 used in this study were 760 and 318 m(2) g(-1) (N2 adsorption). …

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Inconsistent treatment estimates from mis-specified logistic regression analyses of randomized trials

. . Matthews JN, Badi NH. . Stat Med. 2015 Aug 30;34(19):2681-94. doi: 10.1002/sim.6508. Epub 2015 Apr 14. Abstract When the difference between treatments in a clinical trial is estimated by a difference in means, then it is well known that randomization ensures unbiassed estimation, even if no account is taken of important baseline covariates. …

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Breast cancer burden in Africa: evidence from GLOBOCAN 2018

. . Sharma R. . J Public Health (Oxf). 2020 Jul 13:fdaa099. doi: 10.1093/pubmed/fdaa099. Online ahead of print. Abstract BACKGROUND: Breast cancer is the leading malignancy in African females. This study aims to examine the breast cancer burden in Africa using recently released GLOBOCAN 2018 estimates. METHODS: The incidence and mortality estimates of age- and …

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