LibyaMed

Functional and genetic evidence that nucleoside transport is highly conserved in Leishmania species: Implications for pyrimidine-based chemotherapy

. . Alzahrani KJH, Ali JAM, Eze AA, Looi WL, Tagoe DNA, Creek DJ, Barrett MP, de Koning HP. . Int J Parasitol Drugs Drug Resist. 2017 Aug;7(2):206-226. doi: 10.1016/j.ijpddr.2017.04.003. Epub 2017 Apr 20. Abstract Leishmania pyrimidine salvage is replete with opportunities for therapeutic intervention with enzyme inhibitors or antimetabolites. Their uptake into cells depends …

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Intimate partner violence among Arab women before and during the COVID-19 lockdown

. . El-Nimr NA, Mamdouh HM, Ramadan A, El Saeh HM, Shata ZN. . J Egypt Public Health Assoc. 2021 Jun 16;96:15. doi: 10.1186/s42506-021-00077-y. 2021 Dec. Abstract INTRODUCTION: Intimate partner violence (IPV) remains a serious human rights violation and an important health concern during the ongoing COVID-19 pandemic. The study aims to estimate the proportion …

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Canagliflozin inhibits interleukin-1β-stimulated cytokine and chemokine secretion in vascular endothelial cells by AMP-activated protein kinase-dependent and -independent mechanisms

. . Mancini SJ, Boyd D, Katwan OJ, Strembitska A, Almabrouk TA, Kennedy S, Palmer TM, Salt IP. . Sci Rep. 2018 Mar 27;8(1):5276. doi: 10.1038/s41598-018-23420-4. Abstract Recent clinical trials of the hypoglycaemic sodium-glucose co-transporter-2 (SGLT2) inhibitors, which inhibit renal glucose reabsorption, have reported beneficial cardiovascular outcomes. Whether SGLT2 inhibitors directly affect cardiovascular tissues, however, …

Canagliflozin inhibits interleukin-1β-stimulated cytokine and chemokine secretion in vascular endothelial cells by AMP-activated protein kinase-dependent and -independent mechanisms Read More »

Comparison of analog insulin mix 50:50 with human insulin mix 30:70 in persons with type 2 diabetes during Ramadan

. . Hajjaji IM, Eshwihdi N, Barrowman N. . Int J Clin Pract. 2019 Jun;73(6):e13348. doi: 10.1111/ijcp.13348. Epub 2019 Apr 29. Abstract AIM OF THE STUDY: To test if changing the Iftar insulin to a 50:50 mixed analog insulin from a 30:70 human insulin at the same total dose leads to improvement in the postprandial …

Comparison of analog insulin mix 50:50 with human insulin mix 30:70 in persons with type 2 diabetes during Ramadan Read More »

Neuroprotective Effects of 7-Geranyloxycinnamic Acid from Melicope lunu ankenda Leaves

. . Abdulwanis Mohamed Z, Mohamed Eliaser E, Jaafaru MS, Nordin N, Ioannides C, Abdull Razis AF. . Molecules. 2020 Aug 15;25(16):3724. doi: 10.3390/molecules25163724. Abstract Neurodegenerative diseases (NDDs) are chronic conditions that have drawn robust interest from the scientific community. Phytotherapeutic agents are becoming an important source of chemicals for the treatment and management of …

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Clinical features and outcomes of neonatal dengue at the Children’s Hospital 1, Ho Chi Minh, Vietnam

. . Nguyen TM, Huan VT, Reda A, Morsy S, Nam Giang HT, Tri VD, Mau NK, Elfaituri MK, Hieu TH, Hung NT, Hirayama K, Huy NT. . J Clin Virol. 2021 May;138:104758. doi: 10.1016/j.jcv.2021.104758. Epub 2021 Feb 9. Abstract Objectives Neonatal dengue has been reported in the literature with contradictory findings of clinical characteristics …

Clinical features and outcomes of neonatal dengue at the Children’s Hospital 1, Ho Chi Minh, Vietnam Read More »

A novel process to improve the characteristics of low-fat ice cream using date fiber powder

. . Mansour AIA, Ahmed MA, Elfaruk MS, Alsaleem KA, Hammam ARA, El-Derwy YMA. . Food Sci Nutr. 2021 May 1;9(6):2836-2842. doi: 10.1002/fsn3.2159. 2021 Jun. Abstract The objective of this study was to improve the characteristics of low-fat ice cream (LFIC) using date fiber powder (DFP). DFP was added to LFIC mix (3% fat, 14% …

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Development of polymorphic EST microsatellite markers for the sand fly, Phlebotomus papatasi (Diptera: Psychodidae)

. . Hamarsheh O, Karakuş M, Azmi K, Jaouadi K, Yaghoobi-Ershadi MR, Krüger A, Amro A, Kenawy MA, Dokhan MR, Abdeen Z, McDowell MA. . Parasit Vectors. 2018 Mar 9;11(1):160. doi: 10.1186/s13071-018-2770-3. Abstract BACKGROUND: Phlebotomus papatasi is a widely distributed sand fly species in different tropical and sub-tropical regions including the Middle East and North …

Development of polymorphic EST microsatellite markers for the sand fly, Phlebotomus papatasi (Diptera: Psychodidae) Read More »

Clinical utility of reverse phase protein array for molecular classification of breast cancer

. . Negm OH, Muftah AA, Aleskandarany MA, Hamed MR, Ahmad DA, Nolan CC, Diez-Rodriguez M, Tighe PJ, Ellis IO, Rakha EA, Green AR. . Breast Cancer Res Treat. 2016 Jan;155(1):25-35. doi: 10.1007/s10549-015-3654-2. Epub 2015 Dec 9. Abstract Reverse Phase Protein Array (RPPA) represents a sensitive and high-throughput technique allowing simultaneous quantitation of protein expression …

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A novel chemically modified curcumin reduces inflammation-mediated connective tissue breakdown in a rat model of diabetes: periodontal and systemic effects

. . Elburki MS, Moore DD, Terezakis NG, Zhang Y, Lee HM, Johnson F, Golub LM. . J Periodontal Res. 2017 Apr;52(2):186-200. doi: 10.1111/jre.12381. Epub 2016 Apr 1. Abstract BACKGROUND AND OBJECTIVE: Periodontal disease is the most common chronic inflammatory disease known to mankind (and the major cause of tooth loss in the adult population) …

A novel chemically modified curcumin reduces inflammation-mediated connective tissue breakdown in a rat model of diabetes: periodontal and systemic effects Read More »