LibyaMed

Sesamin attenuates neurotoxicity in mouse model of ischemic brain stroke

. . Ahmad S, Elsherbiny NM, Haque R, Khan MB, Ishrat T, Shah ZA, Khan MM, Ali M, Jamal A, Katare DP, Liou GI, Bhatia K. . Neurotoxicology. 2014 Dec;45:100-10. doi: 10.1016/j.neuro.2014.10.002. Epub 2014 Oct 12. Abstract The great saphenous vein (GSV) graft remains a frequently used conduit for coronary artery bypass graft (CABG) surgery. …

Sesamin attenuates neurotoxicity in mouse model of ischemic brain stroke Read More »

New hybrid molecules combining benzothiophene or benzofuran with rhodanine as dual COX-1/2 and 5-LOX inhibitors: Synthesis, biological evaluation and docking study

. . El-Miligy MMM, Hazzaa AA, El-Messmary H, Nassra RA, El-Hawash SAM. . Bioorg Chem. 2017 Jun;72:102-115. doi: 10.1016/j.bioorg.2017.03.012. Epub 2017 Mar 31. Abstract Aim: Colorectal cancer (CRC) is one of the leading cancers in the world. Even though its mortality and pathophysiology are well documented in the US and the European countries, it is …

New hybrid molecules combining benzothiophene or benzofuran with rhodanine as dual COX-1/2 and 5-LOX inhibitors: Synthesis, biological evaluation and docking study Read More »

Febrile rhabdomyolysis of unknown origin in refugees coming from West Africa through the Mediterranean

. . Odolini S, Gobbi F, Zammarchi L, Migliore S, Mencarini P, Vecchia M, di Lauria N, Schivazappa S, Sabatini T, Chianura L, Vanino E, Piacentini D, Zanotti P, Bussi A, Bartoloni A, Bisoffi Z, Castelli F. . Int J Infect Dis. 2017 Sep;62:77-80. doi: 10.1016/j.ijid.2017.07.018. Epub 2017 Jul 26. Abstract Stroke is a severe …

Febrile rhabdomyolysis of unknown origin in refugees coming from West Africa through the Mediterranean Read More »

EPA:DHA 6:1 prevents angiotensin II-induced hypertension and endothelial dysfunction in rats: role of NADPH oxidase- and COX-derived oxidative stress

. . Niazi ZR, Silva GC, Ribeiro TP, León-González AJ, Kassem M, Mirajkar A, Alvi A, Abbas M, Zgheel F, Schini-Kerth VB, Auger C. . Hypertens Res. 2017 Dec;40(12):966-975. doi: 10.1038/hr.2017.72. Epub 2017 Sep 7. Abstract New molecular hybrids combining benzothiophene or its bioisostere benzofuran with rhodanine were synthesized as potential dual COX-2/5-LOX inhibitors. The …

EPA:DHA 6:1 prevents angiotensin II-induced hypertension and endothelial dysfunction in rats: role of NADPH oxidase- and COX-derived oxidative stress Read More »

An ex vivo abomasal ovine model to study the immediate immune response in the context of Haemonchus contortus larval-stage

. . El-Ashram S, Li C, Abouhajer F, Mehmood R, Al Nasr I, Zhang Y, Lu T, Yili D, Suo X, Haoji Z, Li Z, Huang S. . Vet Parasitol. 2018 Apr 30;254:105-113. doi: 10.1016/j.vetpar.2018.02.042. Epub 2018 Mar 1. Abstract OBJECTIVES: Cases of undiagnosed severe febrile rhabdomyolysis in refugees coming from West Africa, mainly from …

An ex vivo abomasal ovine model to study the immediate immune response in the context of Haemonchus contortus larval-stage Read More »

Oral Diclofenac Potassium Versus Hyoscine-N-Butyl Bromide in Reducing Pain Perception during Office Hysteroscopy: ARandomized Double-blind Placebo-controlled Trial

. . Abbas AM, Elzargha AM, Ahmed AGM, Mohamed II, Altraigey A, Abdelbadee AY. . J Minim Invasive Gynecol. 2019 May-Jun;26(4):709-716. doi: 10.1016/j.jmig.2018.08.001. Epub 2018 Aug 10. Abstract Eicosapentaenoic acid:docosahexaenoic acid (EPA:DHA) 6:1, an omega-3 polyunsaturated fatty acid formulation, has been shown to induce a sustained formation of endothelial nitric oxide (NO) synthase-derived NO, a …

Oral Diclofenac Potassium Versus Hyoscine-N-Butyl Bromide in Reducing Pain Perception during Office Hysteroscopy: ARandomized Double-blind Placebo-controlled Trial Read More »

Proton pump inhibitors’ use and risk of hip fracture: a systematic review and meta-analysis

. . Hussain S, Siddiqui AN, Habib A, Hussain MS, Najmi AK. . Rheumatol Int. 2018 Nov;38(11):1999-2014. doi: 10.1007/s00296-018-4142-x. Epub 2018 Aug 29. Abstract We have set up an ex vivo ovine abomasal model, which can mimic the multicellular process to explore the early steps in haemonchine nematode infection using RNA-seq technology. Ovine abomasal explants …

Proton pump inhibitors’ use and risk of hip fracture: a systematic review and meta-analysis Read More »

Oral iron exacerbates colitis and influences the intestinal microbiome

. . Mahalhal A, Williams JM, Johnson S, Ellaby N, Duckworth CA, Burkitt MD, Liu X, Hold GL, Campbell BJ, Pritchard DM, Probert CS. . PLoS One. 2018 Oct 11;13(10):e0202460. doi: 10.1371/journal.pone.0202460. 2018. Abstract STUDY OBJECTIVE: To compare the efficacy of oral diclofenac potassium versus hyoscine-N-butyl bromide (HBB) in reducing pain perception in patients undergoing …

Oral iron exacerbates colitis and influences the intestinal microbiome Read More »

The expression and prognostic value of stem cell markers Bmi-1, HESC5:3, and HES77 in human papillomavirus-positive and -negative oropharyngeal squamous cell carcinoma

. . Mohamed H, Hagström J, Jouhi L, Atula T, Almangush A, Mäkitie A, Haglund C. . Tumour Biol. 2019 Mar;41(3):1010428319840473. doi: 10.1177/1010428319840473. Abstract In the last decade, epidemiological studies presented inconsistent findings concerning the proton pump inhibitors (PPI) use and the risk of hip fracture. So, this systematic review and meta-analysis were performed with …

The expression and prognostic value of stem cell markers Bmi-1, HESC5:3, and HES77 in human papillomavirus-positive and -negative oropharyngeal squamous cell carcinoma Read More »

Use of histograms to assess the efficacy of uterotonic treatment for post-partum haemorrhage: A feasibility study

. . Aflaifel NB, Chandhiok N, Fawole B, Geller SE, Weeks AD. . Best Pract Res Clin Obstet Gynaecol. 2019 Nov;61:15-27. doi: 10.1016/j.bpobgyn.2019.04.008. Epub 2019 May 21. Abstract Inflammatory bowel disease (IBD) is associated with anaemia and oral iron replacement to correct this can be problematic, intensifying inflammation and tissue damage. The intestinal microbiota also …

Use of histograms to assess the efficacy of uterotonic treatment for post-partum haemorrhage: A feasibility study Read More »