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Original article English Buhmeida A, Ristamaki R, Lamlum H, Bendardaf R, Heikkila S, Collan Y, Syrjanen K, Pyrhonen S. Departments of Oncology and Radiotherapy, Turku University Central Hospital, Finland. abuhme@utu.fi Anticancer Res. 2005 Jul-Aug;25(4):3083-8. Abstract BACKGROUND: The prognostic value of morphometric nuclear features in Dukes’ Stages B/C and D colorectal cancer (CRC) was assessed. PATIENTS …

Nuclear area is a prognostic determinant in advanced colorectal cancer. Read More »

Original article English Buhmeida A, Algars A, Ristamaki R, Collan Y, Syrjanen K, Pyrhonen S. Department of Oncology and Radiotherapy, Turku University Hospital, University of Turku, Finland. abuhme@utu.fi Anticancer Res. 2006 Jan-Feb;26(1B):455-62. Abstract BACKGROUND: The prognostic value of morphometric nuclear features was assessed in stage II and stage III colorectal cancer (CRC). MATERIALS AND METHODS: …

Nuclear size as prognostic determinant in stage II and stage III colorectal adenocarcinoma. Read More »

Original article English Buhmeida A, Pyrhonen S, Laato M, Collan Y. Departments of Oncology and Radiotherapy, Turku University Hospital, Turku, Finland. abuhme@utu.fi. Diagn Pathol. 2006 Apr 3;1:4 Abstract Prognostic factors in organ confined prostate cancer will reflect survival after surgical radical prostatectomy. Gleason score, tumour volume, surgical margins and Ki-67 index have the most significant …

Prognostic factors in prostate cancer. Read More »

Original article English Buhmeida A, Algars A, Ristamaki R, Collan Y, Syrjanen K, Pyrhonen S. Department of Oncology and Radiotherapy, Turku University Hospital, University of Turku, Turku, Finland. Oncology. 2007 Jan 12;70(6):427-437 Abstract Background: We assessed the prognostic value of the nuclear DNA content measured in the primary tumours of 123 patients with stage II …

DNA Image Cytometry Is a Useful Adjunct Tool in the Prediction of Disease Outcome in Patients with Stage II and Stage III Colorectal Cancer. Read More »

Original article English Tencer J, Bakoush O, Torffvit O. Department of Nephrology, Lund University Hospital, S-221 85, Lund, Sweden. jan.tencer@njur.lu.se Clin Chim Acta. 2000 Jul;297(1-2):73-83. Abstract The proteinuria selectivity index (SI) describes changes of the glomerular permeability for macromolecules. In the present study, we examine the implications of SI as a diagnostic (199 patients) and …

Diagnostic and prognostic significance of proteinuria selectivity index in glomerular diseases. Read More »

Original article English Bakoush O, Torffvit O, Rippe B, Tencer J. Department of Nephrology, Lund University Hospital, Lund, Sweden. Nephrol Dial Transplant. 2001 Jul;16(7):1357-63. Abstract BACKGROUND: The transport of large proteins across the glomerular capillary wall (GCW) may increase several fold in glomerular diseases. The occurrence of IgM in urine is a consequence of the …

High proteinuria selectivity index based upon IgM is a strong predictor of poor renal survival in glomerular diseases. Read More »

Original article English Bakoush O, Grubb A, Rippe B, Tencer J. Department of Nephrology, Lund University Hospital, Klinikgatan 18, S-221 85 Lund, Sweden. omran.bakoush@skane.se Kidney Int. 2001 Nov;60(5):1904-9. Abstract BACKGROUND: Proteinuric glomerular diseases often are associated with tubulointerstitial injury, which imposes on the progression of renal failure. Tubular damage is partly referable to toxic effects …

Urine excretion of protein HC in proteinuric glomerular diseases correlates to urine IgG but not to albuminuria. Read More »

Original article English Bakoush O, Tencer J, Tapia J, Rippe B, Torffvit O. Department of Nephrology and Department of Medicine, Lund University Hospital, Lund, Sweden. Omran.Bakoush@skane.se Kidney Int. 2002 Jan;61(1):203-8. Abstract BACKGROUND: Proteinuria, due to impairment of the charge- and/or size selectivity of the glomerular capillary wall (GCW) is the earliest clinical evidence of diabetic …

Higher urinary IgM excretion in type 2 diabetic nephropathy compared to type 1 diabetic nephropathy. Read More »

Original article English Bakoush O, Torffvit O, Rippe B, Tencer J. Department of Nephrology, Lund University Hospital, Sweden. Omran.Bakoush@skane.se Clin Nephrol. 2003 May;59(5):345-52. Abstract Renal function in proteinuric glomerular diseases correlates to the changes in urine IgM but not to the changes in the degree of albuminuria. BACKGROUND: Albuminuria is believed to correlate to the …

Renal function in proteinuric glomerular diseases correlates to the changes in urine IgM excretion but not to the changes in the degree of albuminuria. Read More »

Original article English Bakoush O, Tencer J, Torffvit O, Tenstad O, Skogvall I, Rippe B. Department of Nephrology, Lund University Hospital, Lund, Sweden. Omran.Bakoush@skane.se Nephrol Dial Transplant. 2004 Jul;19(7):1724-31. Abstract BACKGROUND: Severe long-standing hypertension is associated with an increased urinary protein excretion. METHODS: To investigate the mechanisms of this proteinuria, we measured the glomerular clearances …

Increased glomerular albumin permeability in old spontaneously hypertensive rats. Read More »