LibyaMed

Toxoplasma gondii infection among chronic hepatitis C patients: a case-control study

. . El-Nahas HA, El-Tantawy NL, Farag RE, Alsalem AM. . Asian Pac J Trop Med. 2014 Aug;7(8):589-593. doi: 10.1016/S1995-7645(14)60100-0. Abstract OBJECTIVE: To determine the detection rate of anti-Toxoplasma gondii (T. gondii) IgG and IgM in chronic HCV patients attending the Department of Tropical Medicine Mansoura University hospital in Egypt. METHODS: This study included 120 …

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The preparation and evaluation of self-nanoemulsifying systems containing Swietenia oil and an examination of its anti-inflammatory effects

. . Eid AM, El-Enshasy HA, Aziz R, Elmarzugi NA. . Int J Nanomedicine. 2014 Oct 7;9:4685-95. doi: 10.2147/IJN.S66180. 2014. Abstract There is an increasing trend among pharmaceutical industries to use natural bioactive materials as medicinal agents and to use new technologies such as self-nanoemulsifying systems. The solubility and bioavailability of poorly soluble drugs can …

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Further evidence to support bimodality of oestrogen receptor expression in breast cancer

. . Muftah AA, Aleskandarany M, Sonbul SN, Nolan CC, Diez Rodriguez M, Caldas C, Ellis IO, Green AR, Rakha EA. . Histopathology. 2017 Feb;70(3):456-465. doi: 10.1111/his.13089. Epub 2016 Nov 28. Abstract AIMS: Although oestrogen receptor (ER)-negative breast cancers (BCs) do not respond to hormone therapy, the response of ER-positive BCs is reported to be …

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Efficacy of azithromycin and metronidazole combined therapy on rats’ gingival overgrowth induced by cyclosporine-A: An experimental animal study

. . Elkabir MA, El-Zehery RR, Mourad MI, Soliman O, Helal ME, Refai AK, Grawish ME. . J Oral Biol Craniofac Res. 2016 Sep-Dec;6(3):219-226. doi: 10.1016/j.jobcr.2016.03.003. Epub 2016 Apr 5. Abstract AIMS: To evaluate the therapeutic efficacy of azithromycin (azm) and/or metronidazole (mtz) on the histopathological features of rats’ gingival overgrowth (GO) induced by cyclosporine-A …

Efficacy of azithromycin and metronidazole combined therapy on rats’ gingival overgrowth induced by cyclosporine-A: An experimental animal study Read More »

NSAIDs as potential treatment option for preventing amyloid β toxicity in Alzheimer’s disease: an investigation by docking, molecular dynamics, and DFT studies

. . Azam F, Alabdullah NH, Ehmedat HM, Abulifa AR, Taban I, Upadhyayula S. . J Biomol Struct Dyn. 2018 Jun;36(8):2099-2117. doi: 10.1080/07391102.2017.1338164. Epub 2017 Jun 15. Abstract Aggregation of amyloid beta (Aβ) protein considered as one of contributors in development of Alzheimer’s disease (AD). Several investigations have identified the importance of non-steroidal anti-inflammatory drugs …

NSAIDs as potential treatment option for preventing amyloid β toxicity in Alzheimer’s disease: an investigation by docking, molecular dynamics, and DFT studies Read More »

Kidney-on-a-chip: untapped opportunities

. . Ashammakhi N, Wesseling-Perry K, Hasan A, Elkhammas E, Zhang YS. . Kidney Int. 2018 Dec;94(6):1073-1086. doi: 10.1016/j.kint.2018.06.034. Epub 2018 Oct 23. Abstract The organs-on-a-chip technology has shown strong promise in mimicking the complexity of native tissues in vitro and ex vivo, and recently significant advances have been made in applying this technology to studies of …

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Evaluation of tamoxifen and simvastatin as the combination therapy for the treatment of hormonal dependent breast cancer cells

. . Ibrahim AB, Zaki HF, Ibrahim WW, Omran MM, Shouman SA. . Toxicol Rep. 2019 Oct 18;6:1114-1126. doi: 10.1016/j.toxrep.2019.10.016. 2019. Abstract Tamoxifen (TAM) is a nonsteroidal antiestrogen drug, used in the prevention and treatment of all stages of hormone-responsive breast cancer. Simvastatin (SIM), a lipid-lowering agent, has been shown to inhibit cancer cell growth. …

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Susceptibility of Toxoplasma gondii to Ethanolic Extract of Tinospora crispa in Vero Cells

. . Sharif AA, Unyah NZ, Nordin N, Basir R, Wana MN, Alapid Ahmad A, Mustapha T, Majid RA. . Evid Based Complement Alternat Med. 2019 Nov 18;2019:2916547. doi: 10.1155/2019/2916547. 2019. Abstract BACKGROUND: Toxoplasmosis remains widely distributed globally and is one of the major neglected parasitic zoonotic infections. The infection is still endemic in most …

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Revealing the Impact of the Environment on Cistanche salsa: From Global Ecological Regionalization to Soil Microbial Community Characteristics

. . Sun X, Pei J, Lin YL, Li BL, Zhang L, Ahmad B, Huang LF. . J Agric Food Chem. 2020 Aug 12;68(32):8720-8731. doi: 10.1021/acs.jafc.0c01568. Epub 2020 Jul 28. Abstract To understand the regulatory relationship between the environment and Cistanche salsa, here we integrated the macro- and microdimension methods. From a macroperspective, the MaxEnt …

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