LibyaMed

Mecasermin in Insulin Receptor-Related Severe Insulin Resistance Syndromes: Case Report and Review of the Literature

. . Plamper M, Gohlke B, Schreiner F, Woelfle J. . Int J Mol Sci. 2018 Apr 24;19(5):1268. doi: 10.3390/ijms19051268. Abstract Mutations in the insulin receptor (INSR) gene underlie rare severe INSR-related insulin resistance syndromes (SIR), including insulin resistance type A, Rabson⁻Mendenhall syndrome and Donohue syndrome (DS), with DS representing the most severe form of …

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Praziquantel-lipid nanocapsules: an oral nanotherapeutic with potential Schistosoma mansoni tegumental targeting

. . Amara RO, Ramadan AA, El-Moslemany RM, Eissa MM, El-Azzouni MZ, El-Khordagui LK. . Int J Nanomedicine. 2018 Aug 6;13:4493-4505. doi: 10.2147/IJN.S167285. 2018. Abstract PURPOSE: Lipid nanocapsules (LNCs) have shown potential to increase the bioavailability and efficacy of orally administered drugs. However, their intestinal translocation to distal target sites and their implication in pharmacokinetic …

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Warfarin use increases bleeding risk in hemodialysis patients with atrial fibrillation: A meta-analysis of cohort studies

. . Hussain S, Siddiqui AN, Baxi H, Habib A, Hussain MS, Najmi AK. . J Gastroenterol Hepatol. 2019 Jun;34(6):975-984. doi: 10.1111/jgh.14601. Epub 2019 Jan 29. Abstract BACKGROUND AND AIM: Atrial fibrillation is one of the most common comorbid conditions in hemodialysis patients, and warfarin is widely prescribed anticoagulant to prevent thromboembolic complications in such …

Warfarin use increases bleeding risk in hemodialysis patients with atrial fibrillation: A meta-analysis of cohort studies Read More »

Neuroprotective Potential of Secondary Metabolites from Melicope lunu-ankenda (Rutaceae)

. . Abdulwanis Mohamed Z, Mohamed Eliaser E, Mazzon E, Rollin P, Cheng Lian Ee G, Abdull Razis AF. . Molecules. 2019 Aug 27;24(17):3109. doi: 10.3390/molecules24173109. Abstract Plant natural compounds have great potential as alternative medicines for preventing and treating diseases. Melicope lunu-ankenda is one Melicope species (family Rutaceae), which is widely used in traditional …

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Hematologic, lipid profile, immunity, and antioxidant status of growing rabbits fed black seed as natural antioxidants

. . El-Gindy Y, Zeweil H, Zahran S, El-Rahman MA, Eisa F. . Trop Anim Health Prod. 2020 May;52(3):999-1004. doi: 10.1007/s11250-019-02091-x. Epub 2019 Nov 6. Abstract It is known that using antibiotics by way of growth promoters has harmful side effects on both animals and consumer health due to cross-resistance among pathogens and residues in …

Hematologic, lipid profile, immunity, and antioxidant status of growing rabbits fed black seed as natural antioxidants Read More »

A biochemical & biophysical study on in-vitro anti-glycating potential of iridin against d-Ribose modified BSA

. . Nabi R, Alvi SS, Shah MS, Ahmad S, Faisal M, Alatar AA, Khan MS. . Arch Biochem Biophys. 2020 Jun 15;686:108373. doi: 10.1016/j.abb.2020.108373. Epub 2020 Apr 20. Abstract Non-enzymatic protein glycation results in the formation of advanced glycation end products (AGEs) leads to the pathogenesis of long-term diabetic complications. Iridin (ID), an antioxidant, …

A biochemical & biophysical study on in-vitro anti-glycating potential of iridin against d-Ribose modified BSA Read More »

An in-silico analysis of ivermectin interaction with potential SARS-CoV-2 targets and host nuclear importin α

. . Azam F, Taban IM, Eid EEM, Iqbal M, Alam O, Khan S, Mahmood D, Anwar MJ, Khalilullah H, Khan MU. . J Biomol Struct Dyn. 2020 Nov 2:1-14. doi: 10.1080/07391102.2020.1841028. Online ahead of print. Abstract Ivermectin (IVM) is a broad-spectrum antiparasitic agent, having inhibitory potential against wide range of viral infections. It has …

An in-silico analysis of ivermectin interaction with potential SARS-CoV-2 targets and host nuclear importin α Read More »

Array-based measurements of aero-allergen-specific IgE correlate with skin-prick test reactivity in asthma regardless of specific IgG4 or total IgE measurements

. . Hamed A, Todd I, Tighe PJ, Powell RJ, Harrison T, Fairclough LC. . J Immunol Methods. 2021 May;492:112999. doi: 10.1016/j.jim.2021.112999. Epub 2021 Feb 18. Abstract Skin prick testing (SPT) and measurement of serum allergen-specific IgE (sIgE) are used to investigate asthma and other allergic conditions. Measurement of serum total IgE (tIgE) and allergen-specific …

Array-based measurements of aero-allergen-specific IgE correlate with skin-prick test reactivity in asthma regardless of specific IgG4 or total IgE measurements Read More »

T4-like Bacteriophages Isolated from Pig Stools Infect Yersinia pseudotuberculosis and Yersinia pestis Using LPS and OmpF as Receptors

. . Salem M, Pajunen MI, Jun JW, Skurnik M. . Viruses. 2021 Feb 13;13(2):296. doi: 10.3390/v13020296. Abstract The Yersinia bacteriophages fPS-2, fPS-65, and fPS-90, isolated from pig stools, have long contractile tails and elongated heads, and they belong to genus Tequatroviruses in the order Caudovirales. The phages exhibited relatively wide host ranges among Yersinia …

T4-like Bacteriophages Isolated from Pig Stools Infect Yersinia pseudotuberculosis and Yersinia pestis Using LPS and OmpF as Receptors Read More »

A Study of a New Technique of the CT Scan View and Disease Classification Protocol Based on Level Challenges in Cases of Coronavirus Disease

. . Salem Salamh AB, Salamah AA, Akyüz HI. . Radiol Res Pract. 2021 Mar 18;2021:5554408. doi: 10.1155/2021/5554408. 2021. Abstract The chest Computer Tomography (CT scan) is used in the diagnosis of coronavirus disease 2019 (COVID-19) and is an important complement to the Reverse Transcription Polymerase Chain Reaction (RT-PCR) test. The paper aims to improve …

A Study of a New Technique of the CT Scan View and Disease Classification Protocol Based on Level Challenges in Cases of Coronavirus Disease Read More »