LibyaMed

. . Mostafa-Hedeab G, Sati LM, Elnaggar HM, Elgatlawey ZO, Eltwab AA, Elsaghayer WA, Ali H. . Iran J Kidney Dis. 2015 Sep;9(5):361-8. Abstract INTRODUCTION: Olive leaves are traditionally used in the Mediterranean basin in many medical conditions for its potent antioxidant activity. Cyclosporine A, a well-known immunosuppressant, can induce nephrotoxicity through oxidative stress. This …

Ameliorating Effect of Olive Leaf Extract on Cyclosporine-induced Nephrotoxicity in Rats Read More »

. . Shaheen A, Aljebali AM. . Endocrine. 2016 Nov;54(2):276-283. doi: 10.1007/s12020-016-1051-1. Epub 2016 Aug 4. Abstract The aim of this article is to solve an existing controversy over the involvement of uncoupling protein-2 in the impairment of glucose-stimulated insulin secretion induced by chronic exposure of β-cells to palmitate. We analyzed and compared the results …

A hypothetical model to solve the controversy over the involvement of UCP2 in palmitate-induced β-cell dysfunction Read More »

. . Fernández-Santander A, Novillo A, Gaibar M, Romero-Lorca A, Moral P, Sánchez-Cuenca D, Amir N, Chaabani H, Harich N, Esteban ME. . Pharmacogenomics. 2016 Aug;17(13):1415-23. doi: 10.2217/pgs-2016-0016. Epub 2016 Jul 29. Abstract AIM: To describe the diversity of four cytochrome and four sulfotransferase polymorphisms in six north African samples. Scarce data have been compiled …

Cytochrome and sulfotransferase gene variation in north African populations Read More »

. . Chaabane A, Justine JL, Gey D, Bakenhaster MD, Neifar L. . PeerJ. 2016 Aug 16;4:e2233. doi: 10.7717/peerj.2233. 2016. Abstract Little is known of the diversity of the monogenean parasites infesting deep-sea groupers, and there is even less information available about their geographic distributions within the ranges of their hosts. To improve our understanding …

Pseudorhabdosynochus sulamericanus (Monogenea, Diplectanidae), a parasite of deep-sea groupers (Serranidae) occurs transatlantically on three congeneric hosts (Hyporthodus spp.), one from the Mediterranean Sea and two from the western Atlantic Read More »

. . Ashammakhi N, Elkhammas E, Hasan A. . J Biomed Mater Res B Appl Biomater. 2019 Aug;107(6):2006-2018. doi: 10.1002/jbm.b.34292. Epub 2018 Dec 31. Abstract Organ-on-a-chip platforms have recently seen tremendous progress. They have found potential applications in the study of physiology and pathology of tissues, drug toxicity, and development of tissue models for replacement …

Translating advances in organ-on-a-chip technology for supporting organs Read More »

. . Haleyur N, Shahsavari E, Mansur AA, Koshlaf E, Morrison PD, Osborn AM, Ball AS. . MethodsX. 2016 Apr 26;3:364-70. doi: 10.1016/j.mex.2016.04.007. 2016. Abstract Polycyclic aromatic hydrocarbons (PAHs) are a major class of organic hydrocarbons with high molecular weight that originate from both natural and anthropogenic sources. Sixteen PAHs are included in the U.S …

Comparison of rapid solvent extraction systems for the GC-MS/MS characterization of polycyclic aromatic hydrocarbons in aged, contaminated soil Read More »

. . Abiedalla Y, Abdel-Hay K, DeRuiter J, Randall Clark C. . Rapid Commun Mass Spectrom. 2016 Mar 30;30(6):763-72. doi: 10.1002/rcm.7491. Abstract RATIONALE: A number of synthetic cathinones (aminoketones, ‘bath salts’) are tertiary amines containing a cyclic amino group, most commonly pyrrolidine. These totally synthetic compounds can be prepared in a number of regioisomeric designer …

Differentiation of cyclic tertiary amine cathinone derivatives by product ion electron ionization mass spectrometry Read More »

. . Maher AMD, Asaiyah MAM, Brophy C, Griffin CT. . Microb Ecol. 2017 Jan;73(1):211-223. doi: 10.1007/s00248-016-0829-2. Epub 2016 Aug 20. Abstract Bacterial symbionts are increasingly recognised as mediators of ecologically important traits of their animal hosts, with acquisition of new traits possible by uptake of novel symbionts. The entomopathogenic nematode Heterorhabditis downesi associates with …

An Entomopathogenic Nematode Extends Its Niche by Associating with Different Symbionts Read More »

. . Bugaighis I, Tiddeman B, Mattick CR, Hobson R. . Eur J Orthod. 2014 Aug;36(4):365-72. doi: 10.1093/ejo/cjs060. Epub 2012 Nov 20. Abstract This prospective cross-sectional, case-controlled morphometric study assessed three dimensional (3D) facial morphological differences between average faces of 103 children aged 8-12 years; 40 with unilateral cleft lip and palate (UCLP), 23 with …

3D comparison of average faces in subjects with oral clefts Read More »

. . Dolan N, Gavin DP, Eshwika A, Kavanagh K, McGinley J, Stephens JC. . Bioorg Med Chem Lett. 2016 Jan 15;26(2):630-635. doi: 10.1016/j.bmcl.2015.11.058. Epub 2015 Nov 18. Abstract We report the synthesis, antibacterial evaluation of a series of thiourea-containing compounds. 1-(3,5-Bis(trifluoromethyl)phenyl)-3-((S)-(6-methoxyquinolin-4-yl)-((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methyl)thiourea 5, was the most active against a range of Gram-positive and Gram-negative bacteria, …

Synthesis, antibacterial and anti-MRSA activity, in vivo toxicity and a structure-activity relationship study of a quinoline thiourea Read More »