LibyaMed

Influence of iron, deferoxamine and ascorbic acid on gentamicin-induced nephrotoxicity in rats.

Original article English Ben Ismail TH, Ali BH, Bashir AA. Department of Pharmacology, Faculty of Medicine, Al-Arab Medical University, Benghazi, Libya. Gen Pharmacol. 1994 Oct;25(6):1249-52. Abstract 1. Nephrotoxicity was induced in rats by injecting gentamicin intramuscularly (i.m.) at a dose of 80 mg/kg for 6 days. Treated animals demonstrated a typical pattern of nephrotoxicity characterized …

Influence of iron, deferoxamine and ascorbic acid on gentamicin-induced nephrotoxicity in rats. Read More »

Pharmacodynamic and pharmacokinetic interactions between alpha-methylparatyrosine and phenobarbitone.

Original article English Elhwuegi AS. Department of Pharmacology and Biochemistry, Faculty of Pharmacy, Al-Fateh Medical University, Tripoli, Libya. Pharmacology. 1994 Nov;49(5):308-13. Abstract The hypnosis and hypothermia induced by phenobarbitone (100 mg/kg i.p.) were greatly potentiated by combined treatment with alpha-methylparatyrosine (alpha-MPT, 250 mg/kg i.p.). alpha-MPT per se produced sedation and hypothermia. Measurement of blood and …

Pharmacodynamic and pharmacokinetic interactions between alpha-methylparatyrosine and phenobarbitone. Read More »

The influence of various experimental conditions on the expression of naloxone-induced withdrawal symptoms in mice.

Original article English el-Kadi AO, Sharif SI. Department of Pharmacology, Faculty of Medicine, Al-Arab Medical University, Benghazi, Libya. Gen Pharmacol. 1994 Nov;25(7):1505-10. Abstract 1. Physical dependence was induced in mice by repeated injections of increasing doses of morphine for either 4 or 7 days. 2. Withdrawal symptoms induced by naloxone (1 mg/kg, i.p.) given 3 …

The influence of various experimental conditions on the expression of naloxone-induced withdrawal symptoms in mice. Read More »

GABA-transaminase in brain and blood platelets: basic and clinical aspects.

Review English Sherif FM. Department of Pharmacology, University for Medical Sciences, Tripoli, Libya. Prog Neuropsychopharmacol Biol Psychiatry. 1994 Dec;18(8):1219-33. Abstract Several lines of evidence suggest that the major inhibitory neuro-transmitter, gamma-aminobutyric acid (GABA) is involved, both directly and indirectly, in the pathogenesis of certain neurological and psychiatric disorders. The main enzyme responsible for GABA catabolism …

GABA-transaminase in brain and blood platelets: basic and clinical aspects. Read More »

Libyan family with hypercholesterolemia and increased high-density lipoprotein cholesterol in plasma.

Case report English Sheriff DS, el Fakhri M, Ghwarsha K. Department of Biochemistry, Arab Medical University, Benghazi, Libya. Clin Chem. 1994 Dec;40(12):2313-6. Abstract Genetic deficiencies of cholesteryl ester transport protein (CETP) and hepatic lipase activities have been associated with hyperalpha-lipoproteinemias. Here we present a family of 11 members, of which 9, including the father, mother, …

Libyan family with hypercholesterolemia and increased high-density lipoprotein cholesterol in plasma. Read More »

Ten-year incidence (1981-90) of insulin-dependent diabetes in the 0-29-year-old age group in Benghazi, Libya.

Original article English Kadiki OA, Moawad SE. Benghazi Diabetic Clinic, Libya. Diabetes Res Clin Pract. 1994 Dec 31;26(3):223-8. Abstract The incidence of Type 1 diabetes in Benghazi, Libya in the < 30-years age group was prospectively studied during the period 1981-1990. A total of 161 male and 150 female new cases were diagnosed during the …

Ten-year incidence (1981-90) of insulin-dependent diabetes in the 0-29-year-old age group in Benghazi, Libya. Read More »