LibyaMed

A validated LC-MS/MS method for the determination of tolterodine and its metabolite in rat plasma and application to pharmacokinetic study

. . Shaik RP, Puttagunta SB, Kothapalli CB, Awen BZS, Challa BR. . J Pharm Anal. 2013 Dec;3(6):489-499. doi: 10.1016/j.jpha.2013.04.005. Epub 2013 May 24. Abstract Liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was used for simultaneous quantification of tolterodine and its metabolite 5-hydroxy methyl tolterodine in rat plasma. Tolterodine-d6 and 5-hydroxy methyl tolterodine-d14 were used as …

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Assessment of the antigen-specific antibody response induced by mucosal administration of a GnRH conjugate entrapped in lipid nanoparticles

. . Gebril AM, Lamprou DA, Alsaadi MM, Stimson WH, Mullen AB, Ferro VA. . Nanomedicine. 2014 Jul;10(5):971-9. doi: 10.1016/j.nano.2013.12.005. Epub 2013 Dec 27. Abstract Vaccines administered parenterally have been developed against gonadotrophin-releasing hormone (GnRH) for anti-fertility and anti-cancer purposes. The aim of this study was to demonstrate whether mucosal delivery using GnRH immunogens entrapped …

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Dental caries experience and periodontal treatment needs of 10- to 15-year old children with type 1 diabetes mellitus

. . Arheiam A, Omar S. . Int Dent J. 2014 Jun;64(3):150-4. doi: 10.1111/idj.12091. Epub 2014 Feb 8. Abstract AIM: To investigate experience of dental caries and periodontal treatment needs among children with type I diabetes mellitus. MATERIALS AND METHODS: A cross-sectional study design, in which experience of dental caries and the periodontal treatment needs …

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Libyan Thymus capitatus essential oil: antioxidant, antimicrobial, cytotoxic and colon pathogen adhesion-inhibition properties

. . Džamić AM, Nikolić BJ, Giweli AA, Mitić-Ćulafić DS, Soković MD, Ristić MS, Knežević-Vukčević JB, Marin PD. . J Appl Microbiol. 2015 Aug;119(2):389-99. doi: 10.1111/jam.12864. Epub 2015 Jun 28. Abstract AIMS: In the present work, the Libyan wild-growing Thymus capitatus essential oil (EO) was evaluated for its biological properties. METHODS AND RESULTS: Carvacrol (68.19%) …

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Evolutionary dynamics of foot-and-mouth disease virus O/ME-SA/Ind2001 lineage

. . Subramaniam S, Mohapatra JK, Sharma GK, Biswal JK, Ranjan R, Rout M, Das B, Dash BB, Sanyal A, Pattnaik B. . Vet Microbiol. 2015 Aug 5;178(3-4):181-9. doi: 10.1016/j.vetmic.2015.05.015. Epub 2015 May 27. Abstract Foot-and-mouth disease (FMD) virus serotype O Ind2001 lineage within the Middle East-South Asia topotype is the major cause of recent …

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Short-Chain Fatty Acids Regulate Secretion of IL-8 from Human Intestinal Epithelial Cell Lines in vitro

. . Asarat M, Vasiljevic T, Apostolopoulos V, Donkor O. . Immunol Invest. 2015;44(7):678-93. doi: 10.3109/08820139.2015.1085389. Abstract Short-chain fatty acids (SCFAs) including acetate, propionate and butyrate play an important role in the physiological functions of epithelial cells and colonocytes, such as immune response regulation. Human intestinal epithelial cells (IECs) contribute in intestinal immune response via …

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Influence of increment thickness on light transmission, degree of conversion and micro hardness of bulk fill composites

. . Garoushi S, Vallittu P, Shinya A, Lassila L. . Odontology. 2016 Sep;104(3):291-7. doi: 10.1007/s10266-015-0227-0. Epub 2015 Dec 11. Abstract This study evaluated characteristics of light transmission, degree of monomer conversion and surface microhardness of bulk fill, conventional and fiber-reinforced resin based composites (RBCs) through different incremental thicknesses of resin composite. Working hypotheses was …

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The effect of TiO2 concentration on properties of apatite-mullite glass-ceramics for dental use

. . Fathi HM, Johnson A. . Dent Mater. 2016 Feb;32(2):311-22. doi: 10.1016/j.dental.2015.11.012. Epub 2015 Dec 30. Abstract OBJECTIVE: The aim of this study was to evaluate the effect of TiO2 concentration on the properties of apatite-mullite glass-ceramics namely strength and the chemical solubility to comply with the ISO standard recommendations for dental ceramics (BS …

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Regenerative Endodontic Procedures for Traumatized Teeth after Horizontal Root Fracture, Avulsion, and Perforating Root Resorption

. . Saoud TM, Mistry S, Kahler B, Sigurdsson A, Lin LM. . J Endod. 2016 Oct;42(10):1476-82. doi: 10.1016/j.joen.2016.04.028. Epub 2016 Aug 26. Abstract INTRODUCTION: Traumatic injury to the teeth can cause horizontal root fractures and inflammatory root resorptions (external and internal). Traditionally, traumatized teeth with horizontal root fractures resulting in pulp necrosis and inflammatory …

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Infectious bronchitis vaccine virus detection and part-S1 genetic variation following single or dual inoculation in broiler chicks

. . Ball C, Awad F, Hutton S, Forrester A, Baylis M, Ganapathy K. . Avian Pathol. 2017 Jun;46(3):309-318. doi: 10.1080/03079457.2016.1268675. Epub 2017 Feb 8. Abstract An investigation was undertaken of the extent of genetic variation occurring within infectious bronchitis virus (IBV) vaccine strains following vaccination of day-old broiler chicks. Chicks were divided into seven …

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